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“Spicing Up” of the Immune System by Curcumin

Overview of attention for article published in Journal of Clinical Immunology, January 2007
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#11 of 1,844)
  • High Attention Score compared to outputs of the same age (99th percentile)
  • High Attention Score compared to outputs of the same age and source (87th percentile)

Mentioned by

news
19 news outlets
blogs
3 blogs
twitter
128 X users
patent
3 patents
facebook
1 Facebook page
wikipedia
2 Wikipedia pages
googleplus
1 Google+ user
video
8 YouTube creators

Citations

dimensions_citation
461 Dimensions

Readers on

mendeley
389 Mendeley
Title
“Spicing Up” of the Immune System by Curcumin
Published in
Journal of Clinical Immunology, January 2007
DOI 10.1007/s10875-006-9066-7
Pubmed ID
Authors

Ganesh Chandra Jagetia, Bharat B. Aggarwal

Abstract

Curcumin (diferuloylmethane) is an orange-yellow component of turmeric (Curcuma longa), a spice often found in curry powder. Traditionally known for its an antiinflammatory effects, curcumin has been shown in the last two decades to be a potent immunomodulatory agent that can modulate the activation of T cells, B cells, macrophages, neutrophils, natural killer cells, and dendritic cells. Curcumin can also downregulate the expression of various proinflammatory cytokines including TNF, IL-1, IL-2, IL-6, IL-8, IL-12, and chemokines, most likely through inactivation of the transcription factor NF-kappaB. Interestingly, however, curcumin at low doses can also enhance antibody responses. This suggests that curcumin's reported beneficial effects in arthritis, allergy, asthma, atherosclerosis, heart disease, Alzheimer's disease, diabetes, and cancer might be due in part to its ability to modulate the immune system. Together, these findings warrant further consideration of curcumin as a therapy for immune disorders.

X Demographics

X Demographics

The data shown below were collected from the profiles of 128 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 389 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 <1%
Brazil 1 <1%
Portugal 1 <1%
United Kingdom 1 <1%
India 1 <1%
Unknown 383 98%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 59 15%
Student > Master 56 14%
Student > Ph. D. Student 49 13%
Researcher 45 12%
Student > Doctoral Student 24 6%
Other 74 19%
Unknown 82 21%
Readers by discipline Count As %
Agricultural and Biological Sciences 71 18%
Medicine and Dentistry 66 17%
Biochemistry, Genetics and Molecular Biology 39 10%
Pharmacology, Toxicology and Pharmaceutical Science 28 7%
Chemistry 23 6%
Other 64 16%
Unknown 98 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 264. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 January 2024.
All research outputs
#140,192
of 25,758,695 outputs
Outputs from Journal of Clinical Immunology
#11
of 1,844 outputs
Outputs of similar age
#257
of 172,403 outputs
Outputs of similar age from Journal of Clinical Immunology
#1
of 8 outputs
Altmetric has tracked 25,758,695 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,844 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.9. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 172,403 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 8 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them