Title |
Neutrophil and macrophage apoptosis in bronchoalveolar lavage fluid from healthy horses and horses with recurrent airway obstruction (RAO)
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Published in |
BMC Veterinary Research, January 2014
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DOI | 10.1186/1746-6148-10-29 |
Pubmed ID | |
Authors |
Artur Niedzwiedz, Zbigniew Jaworski, Bartlomiej Tykalowski, Marcin Smialek |
Abstract |
Dysregulation of apoptosis has been implicated in a range of diseases including tumors, neurodegenerative and autoimmune diseases, as well as allergic asthma and chronic obstructive pulmonary disease (COPD) in humans. Although it has a different pathophysiology, delayed apoptosis of various inflammatory cells may play a pivotal role in the development of recurrent airway obstruction (RAO) in horses. Reduction of inflammatory cell apoptosis or a dysregulation of this process could lead to chronic inflammation and tissue injury. Therefore, the aim of this study was to investigate the rate of apoptosis and necrosis of neutrophils and macrophages in bronchoalveolar lavage fluid obtained from seven horses suffering from RAO (study group) and seven control horses. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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France | 1 | 2% |
Unknown | 40 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 10 | 24% |
Student > Master | 5 | 12% |
Researcher | 4 | 10% |
Student > Doctoral Student | 3 | 7% |
Student > Postgraduate | 3 | 7% |
Other | 9 | 22% |
Unknown | 7 | 17% |
Readers by discipline | Count | As % |
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Veterinary Science and Veterinary Medicine | 18 | 44% |
Medicine and Dentistry | 6 | 15% |
Biochemistry, Genetics and Molecular Biology | 5 | 12% |
Agricultural and Biological Sciences | 4 | 10% |
Social Sciences | 1 | 2% |
Other | 1 | 2% |
Unknown | 6 | 15% |