| Title |
Asymptomatic infections with highly polymorphic Chlamydia suis are ubiquitous in pigs
|
|---|---|
| Published in |
BMC Veterinary Research, December 2017
|
| DOI | 10.1186/s12917-017-1295-x |
| Pubmed ID | |
| Authors |
Min Li, Martina Jelocnik, Feng Yang, Jianseng Gong, Bernhard Kaltenboeck, Adam Polkinghorne, Zhixin Feng, Yvonne Pannekoek, Nicole Borel, Chunlian Song, Ping Jiang, Jing Li, Jilei Zhang, Yaoyao Wang, Jiawei Wang, Xin Zhou, Chengming Wang |
| Abstract |
Chlamydia suis is an important, globally distributed, highly prevalent and diverse obligate intracellular pathogen infecting pigs. To investigate the prevalence and genetic diversity of C. suis in China, 2,137 nasal, conjunctival, and rectal swabs as well as whole blood and lung samples of pigs were collected in 19 regions from ten provinces of China in this study. We report an overall positivity of 62.4% (1,334/2,137) of C. suis following screening by Chlamydia spp. 23S rRNA-based FRET-PCR and high-resolution melting curve analysis and confirmatory sequencing. For C. suis-positive samples, 33.3 % of whole blood and 62.5% of rectal swabs were found to be positive for the C. suis tetR(C) gene, while 13.3% of whole blood and 87.0% of rectal swabs were positive for the C. suis tet(C) gene. Phylogenetic comparison of partial C. suis ompA gene sequences revealed significant genetic diversity in the C. suis strains. This genetic diversity was confirmed by C. suis-specific multilocus sequence typing (MLST), which identified 26 novel sequence types among 27 examined strains. Tanglegrams based on MLST and ompA sequences provided evidence of C. suis recombination amongst the strains analyzed. Genetically highly diverse C. suis strains are exceedingly prevalent in pigs. As it stands, the potential pathogenic effect of C. suis on pig health and production of C. suis remains unclear and will be the subject of further investigations. Further study is also required to address the transmission of C. suis between pigs and the risk of 'spill-over' and 'spill-back' of infections to wild animals and humans. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 28 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 28 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 6 | 21% |
| Student > Master | 5 | 18% |
| Student > Ph. D. Student | 3 | 11% |
| Student > Doctoral Student | 2 | 7% |
| Professor > Associate Professor | 2 | 7% |
| Other | 3 | 11% |
| Unknown | 7 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Immunology and Microbiology | 4 | 14% |
| Biochemistry, Genetics and Molecular Biology | 4 | 14% |
| Veterinary Science and Veterinary Medicine | 3 | 11% |
| Medicine and Dentistry | 2 | 7% |
| Environmental Science | 1 | 4% |
| Other | 5 | 18% |
| Unknown | 9 | 32% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 December 2017.
All research outputs
#14,832,856
of 23,011,300 outputs
Outputs from BMC Veterinary Research
#1,219
of 3,065 outputs
Outputs of similar age
#248,425
of 437,944 outputs
Outputs of similar age from BMC Veterinary Research
#48
of 93 outputs
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