Title |
“Triple-H” therapy for cerebral vasospasm following subarachnoid hemorrhage
|
---|---|
Published in |
Neurocritical Care, January 2006
|
DOI | 10.1385/ncc:4:1:068 |
Pubmed ID | |
Authors |
Kendall H. Lee, Timothy Lukovits, Jonathan A. Friedman |
Abstract |
The combination of induced hypertension, hypervolemia, and hemodilution (triple-H therapy) is often utilized to prevent and treat cerebral vasospasm after aneurysmal subarachnoid hemorrhage (SAH). Although this paradigm has gained widespread acceptance over the past 20 years, the efficacy of triple-H therapy and its precise role in the management of the acute phase of SAH remains uncertain. In addition, triple-H therapy may carry significant medical morbidity, including pulmonary edema, myocardial ischemia, hyponatremia, renal medullary washout, indwelling catheter-related complications, cerebral hemorrhage, and cerebral edema. This review examines the evidence underlying the implementation of triple-H therapy, and makes practical recommendations for the use of this therapy in patients with aneurysmal SAH. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Germany | 1 | 3% |
Unknown | 29 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 5 | 17% |
Student > Master | 4 | 13% |
Student > Ph. D. Student | 4 | 13% |
Student > Doctoral Student | 3 | 10% |
Professor > Associate Professor | 3 | 10% |
Other | 6 | 20% |
Unknown | 5 | 17% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 13 | 43% |
Neuroscience | 4 | 13% |
Agricultural and Biological Sciences | 2 | 7% |
Nursing and Health Professions | 2 | 7% |
Social Sciences | 1 | 3% |
Other | 0 | 0% |
Unknown | 8 | 27% |