Title |
Evolution of plant virus movement proteins from the 30K superfamily and of their homologs integrated in plant genomes
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Published in |
Virology, January 2015
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DOI | 10.1016/j.virol.2014.12.012 |
Pubmed ID | |
Authors |
Arcady R. Mushegian, Santiago F. Elena |
Abstract |
Homologs of Tobacco mosaic virus 30K cell-to-cell movement protein are encoded by diverse plant viruses. Mechanisms of action and evolutionary origins of these proteins remain obscure. We expand the picture of conservation and evolution of the 30K proteins, producing sequence alignment of the 30K superfamily with the broadest phylogenetic coverage thus far and illuminating structural features of the core all-beta fold of these proteins. Integrated copies of pararetrovirus 30K movement genes are prevalent in euphyllophytes, with at least one copy intact in nearly every examined species, and mRNAs detected for most of them. Sequence analysis suggests repeated integrations, pseudogenizations, and positive selection in those provirus genes. An unannotated 30K-superfamily gene in Arabidopsis thaliana genome is likely expressed as a fusion with the At1g37113 transcript. This molecular background of endopararetrovirus gene products in plants may change our view of virus infection and pathogenesis, and perhaps of cellular homeostasis in the hosts. |
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Geographical breakdown
Country | Count | As % |
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Argentina | 1 | 25% |
Spain | 1 | 25% |
Unknown | 2 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 3 | 75% |
Scientists | 1 | 25% |
Mendeley readers
Geographical breakdown
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Japan | 1 | 1% |
Mexico | 1 | 1% |
Brazil | 1 | 1% |
Unknown | 93 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 24 | 25% |
Student > Master | 18 | 19% |
Researcher | 15 | 16% |
Student > Doctoral Student | 8 | 8% |
Student > Bachelor | 6 | 6% |
Other | 12 | 13% |
Unknown | 13 | 14% |
Readers by discipline | Count | As % |
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Biochemistry, Genetics and Molecular Biology | 14 | 15% |
Nursing and Health Professions | 1 | 1% |
Computer Science | 1 | 1% |
Immunology and Microbiology | 1 | 1% |
Other | 3 | 3% |
Unknown | 17 | 18% |