Title |
ADHD, autism and neuroradiological complications among phenylketonuric children in Upper Egypt
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Published in |
Acta Neurologica Belgica, January 2015
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DOI | 10.1007/s13760-014-0422-8 |
Pubmed ID | |
Authors |
Khaled Saad, Yasser Elserogy, Ahmed A. Abdel rahman, Abdulrahman Abdullah Al-Atram, Ismail L. Mohamad, Tarek T. H. ElMelegy, Geir Bjørklund, Amira A. El-Houfy |
Abstract |
The aim of this study is to evaluate the neuropsychological status in a cohort of children with early and continuously treated phenylketonuria in Assiut, Upper Egypt. The study was implemented in seventy-eight phenylketonuria (PKU) children. Only 34 patients met the inclusion criteria. Investigated patients were evaluated according to detailed history, neurological examination, Childhood Autism Rating Scale, full scale Intelligence Quotient, attention deficit hyperactivity disorder, electroencephalography and magnetic resonance imaging (MRI). This study concluded that the prognosis for early diagnosed children with PKU treated from the first weeks of life is generally good. However, they are at increased risk for neurological complications and behavioral problems. So, neonatal screening for PKU is highly recommended in Egypt, for early detection and management. In addition, neuropsychological and MRI assessments in PKU children should be done. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Egypt | 1 | 20% |
Spain | 1 | 20% |
Unknown | 3 | 60% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 3 | 60% |
Practitioners (doctors, other healthcare professionals) | 1 | 20% |
Scientists | 1 | 20% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Egypt | 2 | 2% |
Denmark | 1 | <1% |
Unknown | 103 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 19 | 18% |
Student > Bachelor | 14 | 13% |
Researcher | 13 | 12% |
Student > Ph. D. Student | 10 | 9% |
Student > Doctoral Student | 9 | 8% |
Other | 22 | 21% |
Unknown | 19 | 18% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 22 | 21% |
Psychology | 20 | 19% |
Nursing and Health Professions | 9 | 8% |
Neuroscience | 8 | 8% |
Social Sciences | 5 | 5% |
Other | 18 | 17% |
Unknown | 24 | 23% |