| Title |
Effect of pre-irradiation with different doses, wavelengths, and application intervals of low-level laser therapy on cytochrome c oxidase activity in intact skeletal muscle of rats
|
|---|---|
| Published in |
Lasers in Medical Science, June 2014
|
| DOI | 10.1007/s10103-014-1616-2 |
| Pubmed ID | |
| Authors |
Gianna Móes Albuquerque-Pontes, Rodolfo de Paula Vieira, Shaiane Silva Tomazoni, Cláudia Oliveira Caires, Victoria Nemeth, Adriane Aver Vanin, Larissa Aline Santos, Henrique Dantas Pinto, Rodrigo Labat Marcos, Jan Magnus Bjordal, Paulo de Tarso Camillo de Carvalho, Ernesto Cesar Pinto Leal-Junior |
| Abstract |
Modulation of cytochrome c oxidase activity has been pointed as a possible key mechanism for low-level laser therapy (LLLT) in unhealthy biological tissues. But recent studies by our research group with LLLT in healthy muscles before exercise found delayed skeletal muscle fatigue development and improved biochemical status in muscle tissue. Therefore, the aim of this study was to evaluate effects of different LLLT doses and wavelengths in cytochrome c oxidase activity in intact skeletal muscle. In this animal experiment, we irradiated the tibialis anterior muscle of rats with three different LLLT doses (1, 3, and 10 J) and wavelengths (660, 830, and 905 nm) with 50 mW power output. After irradiation, the analyses of cytochrome c oxidase expression by immunohistochemistry were analyzed at 5, 10, 30 min and at 1, 2, 12, and 24 h. Our results show that LLLT increased (p < 0.05) cytochrome c oxidase expression mainly with the following wavelengths and doses: 660 nm with 1 J, 830 nm with 3 J, and 905 nm with 1 J at all time points. We conclude that LLLT can increase cytochrome c oxidase activity in intact skeletal muscle and that it contributes to our understanding of how LLLT can enhance performance and protect skeletal muscles against fatigue development and tissue damage. Our findings also lead us to think that the combined use of different wavelengths at the same time can enhance LLLT effects in skeletal muscle performance and other conditions, and it can represent a therapeutic advantage in clinical settings. |
Mendeley readers
The data shown below were compiled from readership statistics for 79 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 1 | 1% |
| Brazil | 1 | 1% |
| Unknown | 77 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 13 | 16% |
| Student > Bachelor | 11 | 14% |
| Student > Ph. D. Student | 9 | 11% |
| Researcher | 8 | 10% |
| Professor > Associate Professor | 6 | 8% |
| Other | 13 | 16% |
| Unknown | 19 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 12 | 15% |
| Sports and Recreations | 8 | 10% |
| Nursing and Health Professions | 6 | 8% |
| Engineering | 6 | 8% |
| Chemistry | 6 | 8% |
| Other | 16 | 20% |
| Unknown | 25 | 32% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 July 2022.
All research outputs
#7,012,293
of 22,957,478 outputs
Outputs from Lasers in Medical Science
#241
of 1,316 outputs
Outputs of similar age
#67,021
of 228,684 outputs
Outputs of similar age from Lasers in Medical Science
#8
of 25 outputs
Altmetric has tracked 22,957,478 research outputs across all sources so far. This one has received more attention than most of these and is in the 68th percentile.
So far Altmetric has tracked 1,316 research outputs from this source. They receive a mean Attention Score of 3.0. This one has done well, scoring higher than 80% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 228,684 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.
We're also able to compare this research output to 25 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 68% of its contemporaries.