| Title |
Bowel ultrasound for predicting surgical management of necrotizing enterocolitis: a systematic review and meta-analysis
|
|---|---|
| Published in |
Pediatric Radiology, December 2017
|
| DOI | 10.1007/s00247-017-4056-x |
| Pubmed ID | |
| Authors |
Alain C. Cuna, Nidhi Reddy, Amie L. Robinson, Sherwin S. Chan |
| Abstract |
Necrotizing enterocolitis (NEC) is a devastating inflammatory disease of the intestinal tract that represents a significant source of morbidity and mortality in preterm infants. Imaging of the abdomen is valuable for timely diagnosis and close monitoring of disease progression in NEC. Bowel ultrasound (US) is increasingly being recognized as an important imaging tool for evaluating NEC that provides additional detail than plain abdominal radiographs. To identify bowel US findings associated with surgical management or death in infants with NEC. We searched Embase, PubMed, and the Cumulative Index to Nursing and Allied Health Literature for studies investigating the association between bowel US findings and surgical management or death in NEC. Selected articles were evaluated for quality of study methodology using the Newcastle-Ottawa Scale, and aggregate statistics for odds ratio (OR) and 95% confidence interval were calculated. Of 521 articles reviewed, 11 articles comprising 748 infants were evaluated for quality. Nine of the studies were retrospective and from single-center experiences. Pooled analysis showed that focal fluid collections (OR 17.9, 3.1-103.3), complex ascites (OR 11.3, 4.2-30.0), absent peristalsis (OR 10.7, 1.7-69.0), pneumoperitoneum (OR 9.6, 1.7-56.3), bowel wall echogenicity (OR 8.6, 3.4-21.5), bowel wall thinning (OR 7.11.6-32.3), absent perfusion (OR 7.0, 2.1-23.8), bowel wall thickening (OR 3.9, 2.4-6.1) and dilated bowel (OR 3.5, 1.8-6.8) were associated with surgery or death in NEC. In contrast, portal venous gas (OR 3.0, 0.8-10.6), pneumatosis intestinalis (OR 2.1, 0.9-5.1), increased bowel perfusion (OR 2.6, 0.6-11.1) and simple ascites (OR 0.54, 0.1-2.5) were not associated with surgery or death. This meta-analysis identified several bowel US findings that are associated and not associated with surgery or death in NEC. Bowel US may be useful for early identification of high-risk infants with NEC who may benefit from more aggressive treatment, including surgery. Future studies are needed to determine whether the addition of bowel US in NEC evaluation would improve outcomes. |
X Demographics
The data shown below were collected from the profiles of 14 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Italy | 1 | 7% |
| India | 1 | 7% |
| Ecuador | 1 | 7% |
| Mexico | 1 | 7% |
| United Kingdom | 1 | 7% |
| Unknown | 9 | 64% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 9 | 64% |
| Practitioners (doctors, other healthcare professionals) | 4 | 29% |
| Science communicators (journalists, bloggers, editors) | 1 | 7% |
Mendeley readers
The data shown below were compiled from readership statistics for 122 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 122 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 13 | 11% |
| Student > Master | 13 | 11% |
| Researcher | 12 | 10% |
| Student > Postgraduate | 11 | 9% |
| Student > Doctoral Student | 11 | 9% |
| Other | 25 | 20% |
| Unknown | 37 | 30% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 59 | 48% |
| Nursing and Health Professions | 7 | 6% |
| Veterinary Science and Veterinary Medicine | 2 | 2% |
| Agricultural and Biological Sciences | 2 | 2% |
| Computer Science | 1 | <1% |
| Other | 5 | 4% |
| Unknown | 46 | 38% |
Attention Score in Context
This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 October 2019.
All research outputs
#3,259,048
of 23,301,510 outputs
Outputs from Pediatric Radiology
#180
of 2,112 outputs
Outputs of similar age
#73,933
of 441,932 outputs
Outputs of similar age from Pediatric Radiology
#5
of 45 outputs
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So far Altmetric has tracked 2,112 research outputs from this source. They receive a mean Attention Score of 3.7. This one has done particularly well, scoring higher than 91% of its peers.
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