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Rat strain differences in brain structure and neurochemistry in response to binge alcohol

Overview of attention for article published in Psychopharmacology, September 2013
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Title
Rat strain differences in brain structure and neurochemistry in response to binge alcohol
Published in
Psychopharmacology, September 2013
DOI 10.1007/s00213-013-3253-z
Pubmed ID
Authors

Natalie M Zahr, Dirk Mayer, Torsten Rohlfing, Oliver Hsu, Shara Vinco, Juan Orduna, Richard Luong, Richard L Bell, Edith V Sullivan, Adolf Pfefferbaum

Abstract

Ventricular enlargement is a robust phenotype of the chronically dependent alcoholic human brain, yet the mechanism of ventriculomegaly is unestablished. Heterogeneous stock Wistar rats administered binge EtOH (3 g/kg intragastrically every 8 h for 4 days to average blood alcohol levels (BALs) of 250 mg/dL) demonstrate profound but reversible ventricular enlargement and changes in brain metabolites (e.g., N-acetylaspartate (NAA) and choline-containing compounds (Cho)).

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 28 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 28 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 4 14%
Researcher 4 14%
Student > Doctoral Student 3 11%
Student > Ph. D. Student 3 11%
Professor 3 11%
Other 5 18%
Unknown 6 21%
Readers by discipline Count As %
Psychology 6 21%
Neuroscience 4 14%
Nursing and Health Professions 2 7%
Medicine and Dentistry 2 7%
Social Sciences 2 7%
Other 3 11%
Unknown 9 32%