| Title |
Larger volume and different functional connectivity of the amygdala in women with premenstrual syndrome
|
|---|---|
| Published in |
European Radiology, December 2017
|
| DOI | 10.1007/s00330-017-5206-0 |
| Pubmed ID | |
| Authors |
Demao Deng, Yong Pang, Gaoxiong Duan, Huimei Liu, Hai Liao, Peng Liu, Yanfei Liu, Shasha Li, Wenfu Chen, Danhong Wen, Chunmei Xuan, Min Li |
| Abstract |
To assess structural and functional changes of the amygdala due to premenstrual syndrome (PMS) using magnetic resonance imaging (MRI). Twenty PMS patients and 21 healthy control (HC) subjects underwent a 6-min resting-state fMRI scan during the luteal phase as well as scanning high-resolution T1-weighted images. Subcortical amygdala-related volume and functional connectivity (FC) were estimated between the two groups. Each subject completed a daily record of severity of problems (DRSP) to measure the severity of clinical symptoms. Greater bilateral amygdalae volumes were found in PMS patients compared with HC subjects, and PMS patients had increased FC between the amygdala and certain regions of the frontal cortex (e.g. medial prefrontal cortex (mPFC), anterior cingulate cortex (ACC), right precentral gyrus), the right temporal pole and the insula, as well as decreased FC between the bilateral amygdalae and the right orbitofrontal cortex and right hippocampus. The strength of FC between the right amygdala and right precentral gyrus, left ACC and left mPFC were significantly and positively correlated with DRSP scores in PMS patients. Our findings may improve our understanding of the neural mechanisms involved in PMS. • Functional and structural MRI used to explore amygdala in PMS patients. • Aberrant amygdala structural and functional connectivity were found in PMS patients. • Amygdala strength FC was positively correlated with individual clinical symptom scores. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Philippines | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 34 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 34 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 6 | 18% |
| Student > Postgraduate | 6 | 18% |
| Student > Bachelor | 5 | 15% |
| Student > Master | 3 | 9% |
| Researcher | 2 | 6% |
| Other | 5 | 15% |
| Unknown | 7 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 7 | 21% |
| Psychology | 5 | 15% |
| Neuroscience | 4 | 12% |
| Nursing and Health Professions | 3 | 9% |
| Sports and Recreations | 2 | 6% |
| Other | 4 | 12% |
| Unknown | 9 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 September 2018.
All research outputs
#18,579,736
of 23,012,811 outputs
Outputs from European Radiology
#2,964
of 4,169 outputs
Outputs of similar age
#328,660
of 440,404 outputs
Outputs of similar age from European Radiology
#48
of 69 outputs
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