Title |
Cervical cancer stem cells: opportunities and challenges
|
---|---|
Published in |
Journal of Cancer Research and Clinical Oncology, January 2015
|
DOI | 10.1007/s00432-014-1905-y |
Pubmed ID | |
Authors |
Ravindresh Chhabra |
Abstract |
Cervical cancer remains a leading cause of cancer-related deaths in women in spite of screening and vaccination programs. The current treatment strategies including chemotherapy and surgery could only prolong the patient's survival rather than provide a permanent cure. In case of advanced cervical cancer, radical surgery remains the only option which not only affects the child-bearing ability of the patient, but also comes with a continual risk of recurrence of the disease. Hence, there is a need to develop innovative therapeutics. The cancer stem cell hypothesis states that a tumor has a hierarchical cellular structure in which only a small subpopulation, referred to as cancer stem cells (CSCs), is capable of tumorigenesis. The CSCs possess the stem-like properties of self-renewal and can differentiate into non-stem tumor cells. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Science communicators (journalists, bloggers, editors) | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Japan | 1 | 2% |
China | 1 | 2% |
Unknown | 56 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 9 | 16% |
Student > Master | 8 | 14% |
Student > Ph. D. Student | 7 | 12% |
Student > Doctoral Student | 5 | 9% |
Researcher | 4 | 7% |
Other | 8 | 14% |
Unknown | 17 | 29% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 15 | 26% |
Medicine and Dentistry | 9 | 16% |
Agricultural and Biological Sciences | 7 | 12% |
Nursing and Health Professions | 3 | 5% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 3% |
Other | 5 | 9% |
Unknown | 17 | 29% |