| Title |
Simulation of short-term pressure regulation during the tilt test in a coupled 3D–0D closed-loop model of the circulation
|
|---|---|
| Published in |
Biomechanics and Modeling in Mechanobiology, January 2015
|
| DOI | 10.1007/s10237-014-0645-x |
| Pubmed ID | |
| Authors |
Kevin D. Lau, C. Alberto Figueroa |
| Abstract |
Short-term fluctuations in arterial pressures arising from normal physiological function are buffered by a negative feedback system known as the arterial baroreflex. Initiated by altered biomechanical stretch in the vessel wall, the baroreflex coordinates a systemic response that alters heart rate, cardiac contractility and peripheral vessel vasoconstriction. In this work, a coupled 3D-0D formulation for the short-term pressure regulation of the systemic circulation is presented. Including the baroreflex feedback mechanisms, a patient-specific model of the large arteries is subjected to a simulated head up tilt test. Comparative simulations with and without baroreflex control highlight the critical role that the baroreflex has in regulating variations in pressures within the systemic circulation. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 69 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 3% |
| Unknown | 67 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 19 | 28% |
| Researcher | 13 | 19% |
| Student > Master | 12 | 17% |
| Student > Bachelor | 5 | 7% |
| Student > Doctoral Student | 3 | 4% |
| Other | 9 | 13% |
| Unknown | 8 | 12% |
| Readers by discipline | Count | As % |
|---|---|---|
| Engineering | 38 | 55% |
| Medicine and Dentistry | 6 | 9% |
| Mathematics | 3 | 4% |
| Physics and Astronomy | 3 | 4% |
| Agricultural and Biological Sciences | 3 | 4% |
| Other | 6 | 9% |
| Unknown | 10 | 14% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 January 2015.
All research outputs
#14,405,036
of 23,849,058 outputs
Outputs from Biomechanics and Modeling in Mechanobiology
#186
of 486 outputs
Outputs of similar age
#183,935
of 357,045 outputs
Outputs of similar age from Biomechanics and Modeling in Mechanobiology
#1
of 6 outputs
Altmetric has tracked 23,849,058 research outputs across all sources so far. This one is in the 38th percentile – i.e., 38% of other outputs scored the same or lower than it.
So far Altmetric has tracked 486 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.2. This one is in the 38th percentile – i.e., 38% of its peers scored the same or lower than it.
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