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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Vaginal type-II mucosa is an inductive site for primary CD8+ T-cell mucosal immunity
|
|---|---|
| Published in |
Nature Communications, January 2015
|
| DOI | 10.1038/ncomms7100 |
| Pubmed ID | |
| Authors |
Yichuan Wang, Yongjun Sui, Shingo Kato, Alison E. Hogg, Jason C. Steel, John C. Morris, Jay A. Berzofsky |
| Abstract |
The structured lymphoid tissues are considered the only inductive sites where primary T-cell immune responses occur. The naïve T cells in structured lymphoid tissues, once being primed by antigen-bearing dendritic cells, differentiate into memory T cells and traffic back to the mucosal sites through the bloodstream. Contrary to this belief, here we show that the vaginal type-II mucosa itself, despite the lack of structured lymphoid tissues, can act as an inductive site during primary CD8(+) T-cell immune responses. We provide evidence that the vaginal mucosa supports both the local immune priming of naïve CD8(+) T cells and the local expansion of antigen-specific CD8(+) T cells, thereby demonstrating a different paradigm for primary mucosal T-cell immune induction. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 25% |
| Unknown | 3 | 75% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Science communicators (journalists, bloggers, editors) | 2 | 50% |
| Members of the public | 1 | 25% |
| Scientists | 1 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 50 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 4% |
| Canada | 1 | 2% |
| Unknown | 47 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 12 | 24% |
| Student > Ph. D. Student | 8 | 16% |
| Student > Master | 4 | 8% |
| Student > Doctoral Student | 3 | 6% |
| Student > Bachelor | 2 | 4% |
| Other | 6 | 12% |
| Unknown | 15 | 30% |
| Readers by discipline | Count | As % |
|---|---|---|
| Immunology and Microbiology | 14 | 28% |
| Agricultural and Biological Sciences | 11 | 22% |
| Biochemistry, Genetics and Molecular Biology | 2 | 4% |
| Veterinary Science and Veterinary Medicine | 2 | 4% |
| Medicine and Dentistry | 2 | 4% |
| Other | 1 | 2% |
| Unknown | 18 | 36% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 June 2015.
All research outputs
#12,849,971
of 22,778,347 outputs
Outputs from Nature Communications
#37,782
of 46,914 outputs
Outputs of similar age
#163,562
of 352,028 outputs
Outputs of similar age from Nature Communications
#496
of 682 outputs
Altmetric has tracked 22,778,347 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 46,914 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 55.6. This one is in the 19th percentile – i.e., 19% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 352,028 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.
We're also able to compare this research output to 682 others from the same source and published within six weeks on either side of this one. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.