| Title |
ICON: The Early Diagnosis of Congenital Immunodeficiencies
|
|---|---|
| Published in |
Journal of Clinical Immunology, March 2014
|
| DOI | 10.1007/s10875-014-0003-x |
| Pubmed ID | |
| Authors |
John Routes, Mario Abinun, Waleed Al-Herz, Jacinta Bustamante, Antonio Condino-Neto, Maria Teresa De La Morena, Amos Etzioni, Eleonora Gambineri, Elie Haddad, Lisa Kobrynski, Francoise Le Deist, Shigeaki Nonoyama, Joao Bosco Oliveira, Elena Perez, Capucine Picard, Nima Rezaei, John Sleasman, Kathleen E. Sullivan, Troy Torgerson |
| Abstract |
Primary immunodeficiencies are intrinsic defects in the immune system that result in a predisposition to infection and are frequently accompanied by a propensity to autoimmunity and/or immunedysregulation. Primary immunodeficiencies can be divided into innate immunodeficiencies, phagocytic deficiencies, complement deficiencies, disorders of T cells and B cells (combined immunodeficiencies), antibody deficiencies and immunodeficiencies associated with syndromes. Diseases of immune dysregulation and autoinflammatory disorder are many times also included although the immunodeficiency in these disorders are often secondary to the autoimmunity or immune dysregulation and/or secondary immunosuppression used to control these disorders. Congenital primary immunodeficiencies typically manifest early in life although delayed onset are increasingly recognized. The early diagnosis of congenital immunodeficiencies is essential for optimal management and improved outcomes. In this International Consensus (ICON) document, we provide the salient features of the most common congenital immunodeficiencies. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Ecuador | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 105 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Portugal | 1 | <1% |
| Norway | 1 | <1% |
| Italy | 1 | <1% |
| Mexico | 1 | <1% |
| Argentina | 1 | <1% |
| Unknown | 100 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Other | 20 | 19% |
| Researcher | 11 | 10% |
| Student > Postgraduate | 10 | 10% |
| Student > Bachelor | 9 | 9% |
| Unspecified | 7 | 7% |
| Other | 29 | 28% |
| Unknown | 19 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 43 | 41% |
| Immunology and Microbiology | 12 | 11% |
| Unspecified | 7 | 7% |
| Biochemistry, Genetics and Molecular Biology | 6 | 6% |
| Agricultural and Biological Sciences | 5 | 5% |
| Other | 6 | 6% |
| Unknown | 26 | 25% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 August 2017.
All research outputs
#15,330,390
of 23,577,654 outputs
Outputs from Journal of Clinical Immunology
#997
of 1,623 outputs
Outputs of similar age
#127,482
of 222,379 outputs
Outputs of similar age from Journal of Clinical Immunology
#14
of 33 outputs
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