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Handbook of Immunosenescence

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Cover of 'Handbook of Immunosenescence'

Table of Contents

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    Book Overview
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    Chapter 2 Lymphocyte Subtypes and Functions in Centenarians as Models for Successful Aging
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    Chapter 3 Mouse Models and Genetics of Immunosenescence
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    Chapter 4 Using Insects as Models of Immunosenescence
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    Chapter 5 Clonal Culture Models of T Cell Senescence
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    Chapter 9 Age, T Cell Homeostasis, and T Cell Diversity in Humans
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    Chapter 11 Age-Related Changes in Subpopulations of Peripheral Blood Lymphocytes in Healthy Japanese Population
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    Chapter 12 Changes of T Cell Receptor (TCR) αβ Repertoire in the Face of Aging and Persistent Infections
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    Chapter 14 Mismatch Repair System and Aging: Microsatellite Instability in Peripheral Blood Cells of the Elderly
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    Chapter 17 Generation and Gene Expression of CD28−CD8 T Cells in Human
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    Chapter 18 Role of Regulatory Subsets During Aging
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    Chapter 19 Transcription Factors in Mature B Cells During Aging
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    Chapter 20 B Cell Repertoire Changes in Mouse Models of Aging
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    Chapter 21 Older Human B Cells and Antibodies
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    Chapter 24 Synergistic Effects of Aging and Stress on Neutrophil Function
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    Chapter 25 Role of Dendritic Cells in Aging
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    Chapter 27 Natural Killer Cells in Human Aging
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    Chapter 32 Associations of Cytokine Polymorphisms with Immunosenescence
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    Chapter 33 Cytokine Polymorphisms, Immunosenescence, and Neurodegeneration
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    Chapter 34 Role of TLR Polymorphisms in Aging and Age-Related Diseases
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    Chapter 39 Age-Related Changes in Type 1 and Type 2 Cytokine Production in Humans
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    Chapter 40 Cytokine Expression and Production Changes in Very Old Age
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    Chapter 41 Neuroendocrine-Immune Network and Its Age-Related Changes
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    Chapter 42 Sex Hormones and Immunosenescence
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    Chapter 45 Inflammaging
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    Chapter 46 Molecular and Cellular Aspects of Macrophage Aging
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    Chapter 48 Role of Immunosenescence in Infections and Sepsis in the Elderly
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    Chapter 49 Beneficial and Detrimental Manifestations of Age on CD8 + T Cell Memory to Respiratory Pathogens
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    Chapter 50 HIV Infection as a Model of Accelerated Immunosenescence
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    Chapter 51 Autoimmunity and Autoimmune Diseases in the Elderly
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    Chapter 52 Autoimmunity: Aging Mouse Model for Autoimmune Diseases
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    Chapter 53 Atherosclerosis: An Age-Dependent Autoimmune Disease
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    Chapter 54 Immuno-Inflammatory Athero-Arteriosclerosis Induced by Elastin Peptides – The Effect of Age
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    Chapter 56 Breast Cancer and Immunosenescence
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    Chapter 63 CMV Infection and Frailty: Immunologic Consequences and Disease Pathogenesis
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    Chapter 64 Osteoporosis, Inflammation, and Aging
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    Chapter 71 Immunosenescence Modulation by Vaccination
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    Chapter 72 Interleukin-7 and Immunorejuvenation
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    Chapter 76 Gene Therapy and Immunosenescence
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    Chapter 79 Study of T Cell Immunosenescence in Various Tissue Compartments
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    Chapter 80 Nonhuman Primate Models of Immunosenescence
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    Chapter 82 T-reg Homeostasis and Functions in Ageing
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    Chapter 84 Humoral Immune Function in Long-Lived Ectotherms, the Reptiles
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    Chapter 87 Diversity of CD28null T Cells in the Elderly: A Glimpse in a Biological Adaptation of Aging
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    Chapter 92 Dendritic Cells and Aging
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    Chapter 93 Influence of Aging on Antigen Uptake and Cytokine Production by Dendritic Cells
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    Chapter 94 Monocytes and Macrophages in the Aged Lung and Heart
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    Chapter 96 Myeloid-Derived Suppressor Cells in Aged Humans
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    Chapter 99 Noncoding RNA and Epigenetic Change in Hematopoietic Stem Cell Aging
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    Chapter 104 Energy to Fight Infection
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    Chapter 107 Mitochondria-Associated Inflammasome Activation and Its Impact on Aging and Age-Related Diseases
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    Chapter 109 Age-Related Changes in Immune Regulation by Noncoding RNAs
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    Chapter 111 Immunoproteasome System in Aging, Lifespan, and Age-Associated Disease
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    Chapter 118 Mechanisms of Naive CD4+ T Cell Maintenance in the Elderly and Its Implications for Autoimmunity
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    Chapter 123 T-Cell Immunity Against Cytomegalovirus in Older Adults
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    Chapter 127 Natural Killer Cells and Health Status: Age, CMV Infection, and Obesity
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    Chapter 127 Natural Killer Cells and Health Status: Age, CMV Infection, and Obesity
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    Chapter 129 Role of Immunosenescence in Coronary Artery Disease
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    Chapter 131 Understanding Immune Senescence, Exhaustion, and Immune Activation in HIV–Tuberculosis Coinfection
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    Chapter 132 Immunosenescence and Ageing in HIV
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    Chapter 135 Manifestations of Sepsis in Older Adults
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    Chapter 137 Immunosenescence and Immunosuppressive Drugs in the Elderly
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    Chapter 140 Age-Associated Alterations on Natural Killer Cells in Acute Myeloid Leukemia Patients
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    Chapter 143 Immune Senescence and Inflammaging in Neurological Diseases
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    Chapter 144 The Increase of the Pro-inflammatory Double Negative (IgD−CD27−) B Cell Subset Is Related to the Severity of Alzheimer’s Disease
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    Chapter 149 Microglial Dysfunction in Brain Aging and Neurodegeneration
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    Chapter 150 Changes in the Immune System in Parkinson’s Disease
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    Chapter 152 Frailty in Old Age is Associated with Altered Cytokine Production in Response to TLR Ligation
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    Chapter 154 Clinical Relevance in Disease States: Heart Failure and Coronary Disease
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    Chapter 163 Gut Microbiota in Elderly’s Health
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    Chapter 165 Aging Immunity and the Impact of Physical Exercise
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    Chapter 166 Senescence Induced by DNA Demethylating Drugs to Treat Solid Tumors
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    Chapter 168 Preclinical Animal Models for Developing Vaccines Against Influenza Infection for the Young and the Elderly
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    Chapter 171 Measuring Immunological Age: From T cell Repertoires to Populations
Attention for Chapter 21: Older Human B Cells and Antibodies
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Chapter title
Older Human B Cells and Antibodies
Chapter number 21
Book title
Handbook of Immunosenescence
Published by
Springer International Publishing, January 2018
DOI 10.1007/978-3-319-64597-1_21-1
Book ISBNs
978-3-31-964597-1
Authors

Deborah K. Dunn-Walters, Joselli Silva O’Hare

Editors

Tamas Fulop, Dr. Claudio Franceschi, Katsuiku Hirokawa, Graham Pawelec

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