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Transcriptional programs define molecular characteristics of innate lymphoid cell classes and subsets

Overview of attention for article published in Nature Immunology, January 2015
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (93rd percentile)
  • Good Attention Score compared to outputs of the same age and source (72nd percentile)

Mentioned by

news
1 news outlet
twitter
7 X users
patent
5 patents
weibo
1 weibo user
facebook
1 Facebook page

Citations

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548 Dimensions

Readers on

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571 Mendeley
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Title
Transcriptional programs define molecular characteristics of innate lymphoid cell classes and subsets
Published in
Nature Immunology, January 2015
DOI 10.1038/ni.3094
Pubmed ID
Authors

Michelle L Robinette, Anja Fuchs, Victor S Cortez, Jacob S Lee, Yaming Wang, Scott K Durum, Susan Gilfillan, Marco Colonna

Abstract

The recognized diversity of innate lymphoid cells (ILCs) is rapidly expanding. Three ILC classes have emerged, ILC1, ILC2 and ILC3, with ILC1 and ILC3 including several subsets. The classification of some subsets is unclear, and it remains controversial whether natural killer (NK) cells and ILC1 cells are distinct cell types. To address these issues, we analyzed gene expression in ILCs and NK cells from mouse small intestine, spleen and liver, as part of the Immunological Genome Project. The results showed unique gene-expression patterns for some ILCs and overlapping patterns for ILC1 cells and NK cells, whereas other ILC subsets remained indistinguishable. We identified a transcriptional program shared by small intestine ILCs and a core ILC signature. We revealed and discuss transcripts that suggest previously unknown functions and developmental paths for ILCs.

X Demographics

X Demographics

The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 571 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Netherlands 3 <1%
United Kingdom 2 <1%
Germany 1 <1%
Italy 1 <1%
Sweden 1 <1%
Czechia 1 <1%
Ireland 1 <1%
Spain 1 <1%
Japan 1 <1%
Other 2 <1%
Unknown 557 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 144 25%
Researcher 113 20%
Student > Master 60 11%
Student > Bachelor 45 8%
Student > Doctoral Student 36 6%
Other 67 12%
Unknown 106 19%
Readers by discipline Count As %
Agricultural and Biological Sciences 154 27%
Immunology and Microbiology 154 27%
Biochemistry, Genetics and Molecular Biology 66 12%
Medicine and Dentistry 56 10%
Neuroscience 10 2%
Other 21 4%
Unknown 110 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 21. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 March 2023.
All research outputs
#1,774,297
of 25,420,980 outputs
Outputs from Nature Immunology
#1,067
of 4,194 outputs
Outputs of similar age
#24,126
of 360,470 outputs
Outputs of similar age from Nature Immunology
#15
of 50 outputs
Altmetric has tracked 25,420,980 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,194 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 35.1. This one has gotten more attention than average, scoring higher than 74% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 360,470 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 93% of its contemporaries.
We're also able to compare this research output to 50 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.