Title |
Eosinophilic Esophagitis Clinical Manifestations and Differential Diagnosis
|
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Published in |
Clinical Reviews in Allergy & Immunology, December 2017
|
DOI | 10.1007/s12016-017-8663-y |
Pubmed ID | |
Authors |
Diana Muñoz-Mendoza, Adrián Chapa-Rodríguez, Sami L. Bahna |
Abstract |
As a chronic inflammatory disease with eosinophilic infiltrate of the esophagus, eosinophilic esophagitis (EoE) causes a variety of gastrointestinal (GI) clinical manifestations. None of the symptoms, endoscopic features, or biopsy findings is pathognomonic of the disease, even with high degrees of esophageal eosinophilia. The pathogenesis has been explored by several studies, yet it still far from being completely understood. Evidence supports a role of allergen-driven Th2 lymphocyte mechanism, though not in every patient. This article addresses the disease's clinical manifestations, endoscopic findings, diagnosis, and differential diagnoses. In addition to the current diagnostic criteria, we summarize some recently emerging procedures that promise of enhancing more precise diagnosis and institution of early appropriate management, with consequent better quality of life and reduction of complications. |
X Demographics
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 34 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 6 | 18% |
Other | 4 | 12% |
Student > Master | 4 | 12% |
Student > Bachelor | 3 | 9% |
Student > Postgraduate | 3 | 9% |
Other | 7 | 21% |
Unknown | 7 | 21% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 16 | 47% |
Biochemistry, Genetics and Molecular Biology | 2 | 6% |
Immunology and Microbiology | 2 | 6% |
Psychology | 2 | 6% |
Computer Science | 1 | 3% |
Other | 3 | 9% |
Unknown | 8 | 24% |