| Title |
Chemotherapy-Induced Cardiotoxicity
|
|---|---|
| Published in |
Current Heart Failure Reports, March 2012
|
| DOI | 10.1007/s11897-012-0083-y |
| Pubmed ID | |
| Authors |
Amir Y. Shaikh, Jeffrey A. Shih |
| Abstract |
Anthracycline-based chemotherapeutics have long been recognized as effective agents for treating a wide range of malignancies. However, their use is not without significant adverse cardiotoxic side effects. Strategies for prevention involve limiting free-radical production and subsequent cardiac myocyte damage. Dexrazoxane remains the most widely studied cardioprotective medication. Alternative agents may reduce cardiotoxicity but may still cause significant cardiovascular problems. The role of β-blockers and angiotensin-converting enzyme inhibitors in the treatment of heart failure is well proven. The role of these medications in the prevention and treatment of chemotherapy-induced cardiotoxicity is not well established. |
Mendeley readers
The data shown below were compiled from readership statistics for 411 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Portugal | 1 | <1% |
| Germany | 1 | <1% |
| Chile | 1 | <1% |
| United Kingdom | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 406 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 72 | 18% |
| Student > Master | 61 | 15% |
| Researcher | 37 | 9% |
| Student > Ph. D. Student | 37 | 9% |
| Student > Postgraduate | 35 | 9% |
| Other | 74 | 18% |
| Unknown | 95 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 149 | 36% |
| Biochemistry, Genetics and Molecular Biology | 36 | 9% |
| Agricultural and Biological Sciences | 32 | 8% |
| Pharmacology, Toxicology and Pharmaceutical Science | 32 | 8% |
| Nursing and Health Professions | 12 | 3% |
| Other | 42 | 10% |
| Unknown | 108 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 April 2022.
All research outputs
#7,752,409
of 23,570,677 outputs
Outputs from Current Heart Failure Reports
#126
of 326 outputs
Outputs of similar age
#52,305
of 157,515 outputs
Outputs of similar age from Current Heart Failure Reports
#1
of 3 outputs
Altmetric has tracked 23,570,677 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 326 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.7. This one is in the 49th percentile – i.e., 49% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 157,515 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 45th percentile – i.e., 45% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 3 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them