| Title |
Difference of clinical course between cases with bone union and those with delayed union following osteoporotic vertebral fractures
|
|---|---|
| Published in |
Archives of Osteoporosis, December 2017
|
| DOI | 10.1007/s11657-017-0411-7 |
| Pubmed ID | |
| Authors |
Hiroyuki Yasuda, Masatoshi Hoshino, Tadao Tsujio, Hidetomi Terai, Takashi Namikawa, Minori Kato, Akira Matsumura, Akinobu Suzuki, Kazushi Takayama, Shinji Takahashi, Hiroaki Nakamura |
| Abstract |
In this prospective multicenter study of osteoporotic vertebral fractures (OVFs), delayed union of OVF at 6-month follow-up caused prolonged pain, QOL impairment, ADL impairment, cognitive status deterioration, and vertebral collapse progression. Delayed union following osteoporotic vertebral fracture displayed as an intravertebral cleft on plain X-rays was reported to be a factor for prolonged severe pain. However, the difference of clinical course between bone union and delayed union cases still remains unclear. The purpose of this study was to identify how OVF delayed union following conventional conservative treatment influences the clinical course with a prospective multicenter study. A total of 324 OVF patients from 25 institutes in Osaka, Japan, were included in the study. At the 6-month follow-up after initial visit to each institute, the patients were classified into bone union and delayed union groups based on plain X-ray findings. The outcome assessments included a VAS for back pain, SF-36 for quality of life (QOL), severity of bed-ridden state for activities of daily living (ADL), MMSE for cognitive functions, and degree of vertebral collapse on plain X-rays. Overall, 280 patients were included into the union group and 44 into the delayed union group. The VAS score at 6 months was significantly worse in the delayed union group (p = 0.01). The scores for the SF-36 scales of physical functioning and bodily pain at 6 months were significantly lower in the delayed union group (p = 0.019, p = 0.01, respectively). The percentage of nearly or completely bed-ridden patients was significantly higher in the delayed union group. The percentage of newly developed cognitive impairment was significantly higher in the delayed union group (p = 0.02). Progression of vertebral collapse during the 6-month follow-up was more pronounced in the delayed union group (p < 0.01). The present results revealed that delayed union following OVF causes prolonged pain, QOL impairment, ADL impairment, cognitive status deterioration, and vertebral collapse progression. |
X Demographics
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Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | 50% |
| Netherlands | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 50% |
| Scientists | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 55 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 55 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 8 | 15% |
| Researcher | 5 | 9% |
| Student > Doctoral Student | 5 | 9% |
| Other | 4 | 7% |
| Professor | 4 | 7% |
| Other | 18 | 33% |
| Unknown | 11 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 16 | 29% |
| Nursing and Health Professions | 9 | 16% |
| Neuroscience | 3 | 5% |
| Unspecified | 3 | 5% |
| Agricultural and Biological Sciences | 2 | 4% |
| Other | 9 | 16% |
| Unknown | 13 | 24% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 January 2018.
All research outputs
#18,581,651
of 23,015,156 outputs
Outputs from Archives of Osteoporosis
#455
of 648 outputs
Outputs of similar age
#330,004
of 441,976 outputs
Outputs of similar age from Archives of Osteoporosis
#10
of 12 outputs
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