| Title |
About a Formamide-Based Origin of Informational Polymers: Syntheses of Nucleobases and Favourable Thermodynamic Niches for Early Polymers
|
|---|---|
| Published in |
Origins of Life and Evolution of Biospheres, November 2006
|
| DOI | 10.1007/s11084-006-9053-2 |
| Pubmed ID | |
| Authors |
Raffaele Saladino, Claudia Crestini, Fabiana Ciciriello, Giovanna Costanzo, Ernesto Di Mauro |
| Abstract |
Formamide NH(2)CHO chemistry provides a unitary frame into which several pieces of the origin-of-life puzzle may be adjusted. Synthetic processes were uncovered which, starting from formamide and prebiotically easily available common catalysts, yield all the necessary nucleic bases precursors, including acyclonucleosides. Formamide allows phosphorylations and trans-phosphorylations, favours the micellar aggregation of surfactants and, most importantly, determines conditions in which the formation of nucleic polymers is thermodynamically favoured. In the detected conditions, the phosphoester bonds are more stable in the polymeric than in the monomeric form, thus allowing formation and survival of informational nucleic polymers. |
Mendeley readers
The data shown below were compiled from readership statistics for 51 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 1 | 2% |
| Pakistan | 1 | 2% |
| Italy | 1 | 2% |
| Brazil | 1 | 2% |
| Canada | 1 | 2% |
| Unknown | 46 | 90% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 8 | 16% |
| Researcher | 7 | 14% |
| Professor > Associate Professor | 6 | 12% |
| Other | 4 | 8% |
| Student > Doctoral Student | 4 | 8% |
| Other | 16 | 31% |
| Unknown | 6 | 12% |
| Readers by discipline | Count | As % |
|---|---|---|
| Chemistry | 19 | 37% |
| Agricultural and Biological Sciences | 9 | 18% |
| Earth and Planetary Sciences | 6 | 12% |
| Physics and Astronomy | 6 | 12% |
| Biochemistry, Genetics and Molecular Biology | 1 | 2% |
| Other | 3 | 6% |
| Unknown | 7 | 14% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 May 2023.
All research outputs
#7,942,395
of 23,906,448 outputs
Outputs from Origins of Life and Evolution of Biospheres
#158
of 476 outputs
Outputs of similar age
#43,099
of 160,422 outputs
Outputs of similar age from Origins of Life and Evolution of Biospheres
#4
of 10 outputs
Altmetric has tracked 23,906,448 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 476 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.0. This one is in the 44th percentile – i.e., 44% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 160,422 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 17th percentile – i.e., 17% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one. This one has scored higher than 6 of them.