| Title |
The genetics of alcohol dependence
|
|---|---|
| Published in |
Current Psychiatry Reports, March 2006
|
| DOI | 10.1007/s11920-006-0015-1 |
| Pubmed ID | |
| Authors |
Danielle M. Dick, Laura J. Bierut |
| Abstract |
Alcohol dependence is a common, complex disorder, which affects millions of people worldwide and causes considerable burden in terms of interpersonal and societal costs. Family, twin, and adoption studies have convincingly demonstrated that genes play an important role in the development of alcohol dependence, with heritability estimates in the range of 50% to 60% for both men and women. A number of studies are under way to identify specific genes involved in the predisposition toward alcohol dependence, and there is reason to be enthusiastic about recent progress. Several associated susceptibility genes are reviewed here, including genes involved in alcohol metabolism, as well as genes involved in GABAergic, endogenous opioid, dopaminergic, cholinergic, and serotonergic transmission. The next challenge will be to further characterize the risk associated with these susceptibility genes, examining how they may be related to comorbid disorders, developmental trajectories of risk, and potential moderation by environmental factors. |
Mendeley readers
The data shown below were compiled from readership statistics for 45 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 45 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 12 | 27% |
| Student > Doctoral Student | 4 | 9% |
| Other | 3 | 7% |
| Student > Ph. D. Student | 3 | 7% |
| Student > Master | 3 | 7% |
| Other | 6 | 13% |
| Unknown | 14 | 31% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 9 | 20% |
| Agricultural and Biological Sciences | 6 | 13% |
| Medicine and Dentistry | 6 | 13% |
| Neuroscience | 2 | 4% |
| Social Sciences | 2 | 4% |
| Other | 3 | 7% |
| Unknown | 17 | 38% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 September 2021.
All research outputs
#8,519,292
of 25,383,344 outputs
Outputs from Current Psychiatry Reports
#706
of 1,274 outputs
Outputs of similar age
#30,876
of 92,126 outputs
Outputs of similar age from Current Psychiatry Reports
#1
of 8 outputs
Altmetric has tracked 25,383,344 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,274 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 21.2. This one is in the 34th percentile – i.e., 34% of its peers scored the same or lower than it.
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We're also able to compare this research output to 8 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them