| Title |
Nocturnal inhibition of lipolysis in man by nicotinic acid and derivatives
|
|---|---|
| Published in |
European Journal of Clinical Pharmacology, January 1979
|
| DOI | 10.1007/bf00644960 |
| Pubmed ID | |
| Authors |
W. Kruse, H. Raetzer, C. C. Heuck, P. Oster, B. Schellenberg, G. Schlierf |
| Abstract |
The effect of nicotinic acid and several derivatives on the nocturnal level of free fatty acids was studied in 12 healthy young women and men. Free fatty acids are an important precursor of plasma triglycerides and their concentration is highest at night. The drugs used were nictinic acid, beta-pyridyl-carbinol, mesoinositol hexanicotinate and xantinol nicotinate. The highest plasma nicotinic acid level was observed with beta-pyridyl-carbinol, but significant reduction in free fatty acids during the entire night was only achieved with inositolhexanicotinate and xantinol nicotinate. There was no correlation between the plasm levels of free fatty acids and nicotinic acid at any sampling time. If prolonged reduction in free fatty acid concentration is desired in the therapy of hyperlipidemias, the inositol and xantinol esters of nicotinic acid appear to be superior to the other preparations. |
Mendeley readers
The data shown below were compiled from readership statistics for 7 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 7 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Professor | 1 | 14% |
| Student > Ph. D. Student | 1 | 14% |
| Professor > Associate Professor | 1 | 14% |
| Student > Master | 1 | 14% |
| Unknown | 3 | 43% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 3 | 43% |
| Biochemistry, Genetics and Molecular Biology | 1 | 14% |
| Unknown | 3 | 43% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 August 2011.
All research outputs
#7,451,584
of 22,780,967 outputs
Outputs from European Journal of Clinical Pharmacology
#826
of 2,557 outputs
Outputs of similar age
#4,077
of 26,073 outputs
Outputs of similar age from European Journal of Clinical Pharmacology
#5
of 20 outputs
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