Title |
New insights into the mechanism of heat shock response activation
|
---|---|
Published in |
Cellular and Molecular Life Sciences, February 2008
|
DOI | 10.1007/s00018-008-7458-y |
Pubmed ID | |
Authors |
I. Shamovsky, E. Nudler |
Abstract |
Heat shock (HS) response is a universal mechanism of protection against adverse environmental conditions. It is manifested mainly by rapid and robust induction of molecular chaperones and other cytoprotective proteins. In higher eukaryotes the activation of the HS response is mediated by a master regulator, heat shock transcription factor 1 (HSF1). Here we outline recent progress in understanding the early steps in HSF1 activation by heat in the context of existing models of HSF1 regulation. |
Mendeley readers
The data shown below were compiled from readership statistics for 190 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Switzerland | 3 | 2% |
United States | 2 | 1% |
Mexico | 2 | 1% |
Norway | 1 | <1% |
Austria | 1 | <1% |
France | 1 | <1% |
United Kingdom | 1 | <1% |
Netherlands | 1 | <1% |
Brazil | 1 | <1% |
Other | 1 | <1% |
Unknown | 176 | 93% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 46 | 24% |
Researcher | 30 | 16% |
Student > Bachelor | 26 | 14% |
Student > Master | 24 | 13% |
Professor | 10 | 5% |
Other | 26 | 14% |
Unknown | 28 | 15% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 76 | 40% |
Biochemistry, Genetics and Molecular Biology | 44 | 23% |
Medicine and Dentistry | 13 | 7% |
Chemistry | 5 | 3% |
Engineering | 4 | 2% |
Other | 15 | 8% |
Unknown | 33 | 17% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 February 2024.
All research outputs
#7,845,540
of 23,794,258 outputs
Outputs from Cellular and Molecular Life Sciences
#1,655
of 4,151 outputs
Outputs of similar age
#44,273
of 160,833 outputs
Outputs of similar age from Cellular and Molecular Life Sciences
#17
of 33 outputs
Altmetric has tracked 23,794,258 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,151 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.0. This one is in the 38th percentile – i.e., 38% of its peers scored the same or lower than it.
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We're also able to compare this research output to 33 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.