| Title |
Sex determination in mammals — Before and after the evolution of SRY
|
|---|---|
| Published in |
Cellular and Molecular Life Sciences, June 2008
|
| DOI | 10.1007/s00018-008-8109-z |
| Pubmed ID | |
| Authors |
M. C. Wallis, P. D. Waters, J. A. M. Graves |
| Abstract |
Therian mammals (marsupials and placentals) have an XX female: XY male sex chromosome system, which is homologous to autosomes in other vertebrates. The testis-determining gene, SRY, is conserved on the Y throughout therians, but is absent in other vertebrates, suggesting that the mammal system evolved about 310 million years ago (MYA). However, recent work on the basal monotreme mammals has completely changed our conception of how and when this change occurred. Platypus and echidna lack SRY, and the therian X and Y are represented by autosomes, implying that SRY evolved in therians after their divergence from monotremes only 166 MYA. Clues to the ancestral mechanism usurped by SRY in therians are provided by the monotremes, whose sex chromosomes are homologous to the ZW of birds. This suggests that the therian X and Y, and the SRY gene, evolved from an ancient bird-like sex chromosome system which predates the divergence of mammals and reptiles 310 MYA. |
Mendeley readers
The data shown below were compiled from readership statistics for 169 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Netherlands | 1 | <1% |
| New Caledonia | 1 | <1% |
| Brazil | 1 | <1% |
| Czechia | 1 | <1% |
| Mexico | 1 | <1% |
| Spain | 1 | <1% |
| Japan | 1 | <1% |
| Unknown | 162 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 38 | 22% |
| Student > Ph. D. Student | 28 | 17% |
| Student > Bachelor | 27 | 16% |
| Student > Master | 27 | 16% |
| Student > Doctoral Student | 8 | 5% |
| Other | 15 | 9% |
| Unknown | 26 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 67 | 40% |
| Biochemistry, Genetics and Molecular Biology | 41 | 24% |
| Neuroscience | 6 | 4% |
| Environmental Science | 5 | 3% |
| Computer Science | 3 | 2% |
| Other | 23 | 14% |
| Unknown | 24 | 14% |
Attention Score in Context
This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 March 2024.
All research outputs
#3,940,289
of 23,794,258 outputs
Outputs from Cellular and Molecular Life Sciences
#714
of 4,151 outputs
Outputs of similar age
#13,209
of 83,683 outputs
Outputs of similar age from Cellular and Molecular Life Sciences
#4
of 31 outputs
Altmetric has tracked 23,794,258 research outputs across all sources so far. Compared to these this one has done well and is in the 83rd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,151 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.0. This one has done well, scoring higher than 83% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 83,683 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 83% of its contemporaries.
We're also able to compare this research output to 31 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 87% of its contemporaries.