Title |
Association of Autism with Maternal Infections, Perinatal and Other Risk Factors: A Case-Control Study
|
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Published in |
Journal of Autism and Developmental Disorders, January 2018
|
DOI | 10.1007/s10803-017-3449-x |
Pubmed ID | |
Authors |
Dikran Richard Guisso, Fadi S. Saadeh, Dahlia Saab, Joud El Deek, Sarah Chamseddine, Hadi Abou El Hassan, Ghidaa Majari, Rose-Mary Boustany |
Abstract |
This case-control study explores the association between pregnancy/birth complications and other factors with Autism Spectrum Disorder (ASD) in Lebanese subjects aged 2-18 years. Researchers interviewed 136 ASD cases from the American University of Beirut Medical Center Special Kids Clinic, and 178 controls selected by systematic digit dialing in the Greater-Beirut area. Male gender (Adjusted Odds Ratio [95% CI]: 3.9 [2.2-7.0]); postpartum feeding difficulties (2.5 [1.2-5.4]); maternal infections/complications during pregnancy (2.9 [1.5-5.5], 2.1 [1.1-3.9]); consanguinity (2.5 [1.0-6.0]); family history of psychiatric disorders (2.2 [1.1-4.4]) were risk factors for ASD. Being born first/second (0.52 [0.28-0.95]) and maternal psychological support during pregnancy (0.49 [0.27-0.89]) were negatively associated with ASD. Identifying ASD correlates is crucial for instigating timely screening and subsequent early intervention. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 3 | 14% |
United Kingdom | 2 | 9% |
Spain | 2 | 9% |
Canada | 1 | 5% |
India | 1 | 5% |
Switzerland | 1 | 5% |
Mexico | 1 | 5% |
Saudi Arabia | 1 | 5% |
Unknown | 10 | 45% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 17 | 77% |
Scientists | 4 | 18% |
Practitioners (doctors, other healthcare professionals) | 1 | 5% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 142 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 17 | 12% |
Student > Bachelor | 17 | 12% |
Student > Ph. D. Student | 15 | 11% |
Student > Doctoral Student | 11 | 8% |
Student > Postgraduate | 11 | 8% |
Other | 20 | 14% |
Unknown | 51 | 36% |
Readers by discipline | Count | As % |
---|---|---|
Psychology | 27 | 19% |
Medicine and Dentistry | 18 | 13% |
Social Sciences | 9 | 6% |
Biochemistry, Genetics and Molecular Biology | 9 | 6% |
Nursing and Health Professions | 7 | 5% |
Other | 10 | 7% |
Unknown | 62 | 44% |