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Inflammation and Cancer

Overview of attention for book
Cover of 'Inflammation and Cancer'

Table of Contents

  1. Altmetric Badge
    Book Overview
  2. Altmetric Badge
    Chapter 1 In Vivo Models of Inflammatory Bowel Disease and Colitis-Associated Cancer
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    Chapter 2 Combining Cell Type-Restricted Adenoviral Targeting with Immunostaining and Flow Cytometry to Identify Cells-of-Origin of Lung Cancer
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    Chapter 3 Utility of Endoscopic Ultrasound-Guided Fine-Needle Aspiration for Preclinical Evaluation of Therapies in Cancer
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    Chapter 4 Modelling Intestinal Carcinogenesis Using In Vitro Organoid Cultures
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    Chapter 5 Protocols to Evaluate Cigarette Smoke-Induced Lung Inflammation and Pathology in Mice
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    Chapter 6 Tracking Competent Host Defence to Chronic Inflammation: An In Vivo Model of Peritonitis
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    Chapter 7 Citrobacter rodentium Infection Model for the Analysis of Bacterial Pathogenesis and Mucosal Immunology
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    Chapter 8 In Vivo Infection Model of Severe Influenza A Virus
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    Chapter 9 In Vivo Models for Inflammatory Arthritis
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    Chapter 10 Isolation of Mouse Primary Gastric Epithelial Cells to Investigate the Mechanisms of Helicobacter pylori Associated Disease
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    Chapter 11 Dissecting Interleukin-6 Classic- and Trans-Signaling in Inflammation and Cancer
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    Chapter 12 Laser Microdissection of Cellular Compartments for Expression Analyses in Cancer Models
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    Chapter 13 Tissue Processing for Stereological Analyses of Lung Structure in Chronic Obstructive Pulmonary Disease
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    Chapter 14 Quantifying Caspase-1 Activity in Murine Macrophages
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    Chapter 15 Analysis of Histone Modifications in Acute Myeloid Leukaemia Using Chromatin Immunoprecipitation
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    Chapter 16 Analysis of DNA Methylation in Tissues Exposed to Inflammation
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    Chapter 17 A Comprehensive Protocol Resource for Performing Pooled shRNA and CRISPR Screens
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    Chapter 18 Immuno-detection of Immature and Bioactive Forms of the Inflammatory Cytokine IL-18
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    Chapter 19 Optimization Techniques for miRNA Expression in Low Frequency Immune Cell Populations
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    Chapter 20 Assessing the cGAS-cGAMP-STING Activity of Cancer Cells
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    Chapter 21 Expression and Purification of JAK1 and SOCS1 for Structural and Biochemical Studies
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    Chapter 22 Production of Recombinant Killer Immunoglobulin-Like Receptors for Crystallography and Luminex-Based Assays
  24. Altmetric Badge
    Chapter 23 Isolation and Characterization of Mouse Intrahepatic Lymphocytes by Flow Cytometry
Attention for Chapter 17: A Comprehensive Protocol Resource for Performing Pooled shRNA and CRISPR Screens
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  • Good Attention Score compared to outputs of the same age and source (66th percentile)

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Citations

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Chapter title
A Comprehensive Protocol Resource for Performing Pooled shRNA and CRISPR Screens
Chapter number 17
Book title
Inflammation and Cancer
Published in
Methods in molecular biology, January 2018
DOI 10.1007/978-1-4939-7568-6_17
Pubmed ID
29322420
Book ISBNs
978-1-4939-7567-9, 978-1-4939-7568-6
Authors

Leonie A. Cluse, Iva Nikolic, Deborah Knight, Piyush B. Madhamshettiwar, Jennii Luu, Karla J. Cowley, Timothy Semple, Gisela Mir Arnau, Jake Shortt, Ricky W. Johnstone, Kaylene J. Simpson, Cluse, Leonie A., Nikolic, Iva, Knight, Deborah, Madhamshettiwar, Piyush B., Luu, Jennii, Cowley, Karla J., Semple, Timothy, Arnau, Gisela Mir, Shortt, Jake, Johnstone, Ricky W., Simpson, Kaylene J.

Abstract

This chapter details a compendium of protocols that collectively enable the reader to perform a pooled shRNA and/or CRISPR screen-with methods to identify and validate positive controls and subsequent hits; establish a viral titer in the cell line of choice; create and screen libraries, sequence strategies, and bioinformatics resources to analyze outcomes. Collectively, this provides an overarching resource from the start to finish of a screening project, making this technology possible in all laboratories.

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X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
 Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 32 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 32 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 8 25%
Researcher 8 25%
Student > Master 4 13%
Student > Bachelor 2 6%
Other 1 3%
Other 2 6%
Unknown 7 22%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 9 28%
Agricultural and Biological Sciences 9 28%
Pharmacology, Toxicology and Pharmaceutical Science 2 6%
Immunology and Microbiology 2 6%
Medicine and Dentistry 2 6%
Other 1 3%
Unknown 7 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 January 2019.
All research outputs
#14,373,275
of 23,016,919 outputs
Outputs from Methods in molecular biology
#4,226
of 13,165 outputs
Outputs of similar age
#240,485
of 442,344 outputs
Outputs of similar age from Methods in molecular biology
#432
of 1,498 outputs
Altmetric has tracked 23,016,919 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,165 research outputs from this source. They receive a mean Attention Score of 3.4. This one has gotten more attention than average, scoring higher than 64% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 442,344 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 42nd percentile – i.e., 42% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 1,498 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.

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