Title |
The embryology of conjoined twins
|
---|---|
Published in |
Child's Nervous System, July 2004
|
DOI | 10.1007/s00381-004-0985-4 |
Pubmed ID | |
Authors |
M. H. Kaufman |
Abstract |
Attention is drawn to the spontaneous incidence of twinning, both dizygotic and monozygotic in different mammalian species. Conjoined twinning, however, only arises when the twinning event occurs at about the primitive streak stage of development, at about 13-14 days after fertilisation in the human, and is exclusively associated with the monoamniotic monochorionic type of placentation. It is believed that the highest incidence of conjoined twinning is encountered in the human. While monozygotic twinning may be induced experimentally following exposure to a variety of agents, the mechanism of induction of spontaneous twinning in the human remains unknown. All agents that are capable of acting as a twinning stimulus are teratogenic, and probably act by interfering with the spindle apparatus. |
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Unknown | 1 | 33% |
Demographic breakdown
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Mendeley readers
Geographical breakdown
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Veterinary Science and Veterinary Medicine | 2 | 2% |
Other | 8 | 7% |
Unknown | 34 | 28% |