Title |
Comparison of the clinical efficacy of flutamide and spironolactone plus ethinyloestradiol/cyproterone acetate in the treatment of hirsutism: A randomised controlled study
|
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Published in |
Advances in Therapy, April 2008
|
DOI | 10.1007/s12325-008-0039-5 |
Pubmed ID | |
Authors |
Feridun Karakurt, Ibrahim Sahin, Serdar Güler, Berrin Demirbas, Cavit Culha, Rustu Serter, Yalcin Aral, Nuket Bavbek |
Abstract |
Hirsutism is commonly a consequence of ovarian androgen over-production. Polycystic ovary syndrome (PCOS) or peripheral hypersensitivity to normal androgen circulating levels (idiopathic hirsutism) can be the underlying cause. Several drugs with anti-androgenic properties, such as cyproterone acetate (CPA), spironolactone and flutamide have been used to treat hirsutism, but the efficacy of these drugs has yet to be fully elucidated. The objective of this study was to compare the effectiveness of flutamide, and spironolactone plus a combination tablet of 2 mg CPA/35 microg ethinyloestradiol (EE) in the treatment of hirsutism. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Singapore | 1 | 6% |
Unknown | 15 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 2 | 13% |
Student > Bachelor | 2 | 13% |
Other | 1 | 6% |
Student > Doctoral Student | 1 | 6% |
Professor > Associate Professor | 1 | 6% |
Other | 1 | 6% |
Unknown | 8 | 50% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 5 | 31% |
Biochemistry, Genetics and Molecular Biology | 2 | 13% |
Nursing and Health Professions | 1 | 6% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 6% |
Unknown | 7 | 44% |