Title |
Spectrum of Epstein-Barr virus-related diseases: a pictorial review
|
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Published in |
Japanese Journal of Radiology, February 2009
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DOI | 10.1007/s11604-008-0291-2 |
Pubmed ID | |
Authors |
Eriko Maeda, Masaaki Akahane, Shigeru Kiryu, Nobuyuki Kato, Takeharu Yoshikawa, Naoto Hayashi, Shigeki Aoki, Manabu Minami, Hiroshi Uozaki, Masashi Fukayama, Kuni Ohtomo |
Abstract |
Epstein-Barr virus (EBV) prevails among more than 90% of the adult population worldwide. Most primary infections occur during young childhood and cause no or only nonspecific symptoms; then the virus becomes latent and resides in lymphocytes in the peripheral blood. Inactive latent EBV usually causes no serious consequences, but once it becomes active it can cause a wide spectrum of malignancies: epithelial tumors such as nasopharyngeal and gastric carcinomas; mesenchymal tumors such as follicular dendritic cell tumor/sarcoma; and lymphoid malignancies such as Burkitt lymphoma, lymphomatoid granulomatosis, pyothorax-associated lymphoma, immunodeficiency-associated lymphoproliferative disorders, extranodal natural killer (NK) cell/T-cell lymphoma, and Hodgkin's lymphoma. The purpose of this article is to describe the spectrum of EBV-related diseases and their key imaging findings. EBV-related lymphoproliferative disorders and lymphomas are especially common in immunocompromised patients. Awareness of their clinical settings and imaging spectrum contributes to early detection and early treatment of possibly life-threatening disorders. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Science communicators (journalists, bloggers, editors) | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Hungary | 1 | <1% |
Switzerland | 1 | <1% |
Brazil | 1 | <1% |
Japan | 1 | <1% |
United States | 1 | <1% |
Unknown | 138 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 28 | 20% |
Student > Bachelor | 25 | 17% |
Student > Ph. D. Student | 18 | 13% |
Researcher | 12 | 8% |
Other | 9 | 6% |
Other | 19 | 13% |
Unknown | 32 | 22% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 40 | 28% |
Agricultural and Biological Sciences | 26 | 18% |
Biochemistry, Genetics and Molecular Biology | 19 | 13% |
Immunology and Microbiology | 11 | 8% |
Chemistry | 3 | 2% |
Other | 9 | 6% |
Unknown | 35 | 24% |