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An Impaired Inflammatory Cytokine Response to Gram-Negative LPS in Human Neonates is Associated with the Defective TLR-Mediated Signaling Pathway

Overview of attention for article published in Journal of Clinical Immunology, January 2015
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age and source (60th percentile)

Mentioned by

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1 X user
facebook
1 Facebook page

Citations

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17 Dimensions

Readers on

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38 Mendeley
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Title
An Impaired Inflammatory Cytokine Response to Gram-Negative LPS in Human Neonates is Associated with the Defective TLR-Mediated Signaling Pathway
Published in
Journal of Clinical Immunology, January 2015
DOI 10.1007/s10875-015-0128-6
Pubmed ID
Authors

Yi Ping Li, Sheng Lin Yu, Zhi Jian Huang, Jie Huang, Jian Pan, Xing Feng, Xue Guang Zhang, Jiang Huai Wang, Jian Wang

Abstract

Human neonates are highly susceptible to a wide range of infections, which has been attributed to deficiencies in their innate and adaptive immunity. In contrast to the well-documented immaturity in neonatal adaptive immunity, deficiencies in their innate immunity are less defined. This study examined the inflammatory response of neonatal monocytes to bacterial lipopolysaccharide (LPS) and peptidoglycan (PGN) stimulation and discriminated the underlying Toll-like receptor (TLR)-mediated signal transduction pathways.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 38 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Mexico 1 3%
India 1 3%
Unknown 36 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 8 21%
Researcher 7 18%
Student > Bachelor 4 11%
Student > Doctoral Student 3 8%
Student > Master 3 8%
Other 7 18%
Unknown 6 16%
Readers by discipline Count As %
Agricultural and Biological Sciences 7 18%
Medicine and Dentistry 7 18%
Biochemistry, Genetics and Molecular Biology 5 13%
Immunology and Microbiology 5 13%
Engineering 2 5%
Other 3 8%
Unknown 9 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 February 2015.
All research outputs
#18,392,390
of 22,782,096 outputs
Outputs from Journal of Clinical Immunology
#1,126
of 1,556 outputs
Outputs of similar age
#257,283
of 353,568 outputs
Outputs of similar age from Journal of Clinical Immunology
#10
of 28 outputs
Altmetric has tracked 22,782,096 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,556 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one is in the 19th percentile – i.e., 19% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 353,568 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 15th percentile – i.e., 15% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 28 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 60% of its contemporaries.