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Essential Concepts in Toxicogenomics

Overview of attention for book
Cover of 'Essential Concepts in Toxicogenomics'

Table of Contents

  1. Altmetric Badge
    Book Overview
  2. Altmetric Badge
    Chapter 1 Toxicogenomics and Classic Toxicology: How to Improve Prediction and Mechanistic Understanding of Human Toxicity
  3. Altmetric Badge
    Chapter 2 Use of Traditional End Points and Gene Dysregulation to Understand Mechanisms of Toxicity: Toxicogenomics in Mechanistic Toxicology
  4. Altmetric Badge
    Chapter 3 Quality Control of Microarray Assays for Toxicogenomic and In Vitro Diagnostic Applications
  5. Altmetric Badge
    Chapter 4 Role of Statistics in Toxicogenomics
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    Chapter 5 Predictive Toxicogenomics in Preclinical Discovery
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    Chapter 6 In Vivo Predictive Toxicogenomics
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    Chapter 7 Bioinformatics: Databasing and Gene Annotation
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    Chapter 8 Microarray Probe Mapping and Annotation in Cross-Species Comparative Toxicogenomics
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    Chapter 9 Toxicogenomics in Biomarker Discovery
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    Chapter 10 From Pharmacogenomics to Translational Biomarkers
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    Chapter 11 Public consortium efforts in toxicogenomics.
  13. Altmetric Badge
    Chapter 12 Applications of Toxicogenomics to Nonclinical Drug Development: Regulatory Science Considerations
Attention for Chapter 11: Public consortium efforts in toxicogenomics.
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Mentioned by

wikipedia
23 Wikipedia pages

Citations

dimensions_citation
4 Dimensions

Readers on

mendeley
10 Mendeley
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1 CiteULike
Summary Wikipedia Dimensions citations
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Chapter title
Public consortium efforts in toxicogenomics.
Chapter number 11
Book title
Essential Concepts in Toxicogenomics
Published in
Methods in molecular biology, May 2008
DOI 10.1007/978-1-60327-048-9_11
Pubmed ID
18449490
Book ISBNs
978-1-58829-638-2, 978-1-60327-048-9
Authors

Mattes WB, Mattes, William B., William B. Mattes

Abstract

Public consortia provide a forum for addressing questions requiring more resources than one organization alone could bring to bear and engaging many sectors of the scientific community. They are particular well suited for tackling some of the questions encountered in the field of toxicogenomics, where the number of studies and microarray analyses would be prohibitively expensive for a single organization to carry out. Five consortia that stand out in the field of toxicogenomics are the Institutional Life Sciences Institute (ILSI) Health and Environmental Sciences Institute (HESI) Committee on the Application of Genomics to Mechanism Based Risk Assessment, the Toxicogenomics Research Consortium, the MicroArray Quality Control (MAQC) Consortium, the InnoMed PredTox effort, and the Predictive Safety Testing Consortium. Collectively, these consortia efforts have addressed issues such as reproducibility of microarray results, standard practice for assays and analysis, relevance of microarray results to conventional end points, and robustness of statistical models on diverse data sets. Their results demonstrate the impact that the pooling of resources, experience, expertise, and insight found in consortia can have.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 10 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 10 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 2 20%
Student > Ph. D. Student 2 20%
Student > Master 2 20%
Professor 1 10%
Librarian 1 10%
Other 2 20%
Readers by discipline Count As %
Medicine and Dentistry 4 40%
Engineering 2 20%
Economics, Econometrics and Finance 1 10%
Business, Management and Accounting 1 10%
Social Sciences 1 10%
Other 1 10%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 March 2023.
All research outputs
#7,731,085
of 23,504,445 outputs
Outputs from Methods in molecular biology
#2,421
of 13,359 outputs
Outputs of similar age
#28,255
of 80,522 outputs
Outputs of similar age from Methods in molecular biology
#4
of 24 outputs
Altmetric has tracked 23,504,445 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,359 research outputs from this source. They receive a mean Attention Score of 3.4. This one has done well, scoring higher than 75% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 80,522 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 18th percentile – i.e., 18% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 24 others from the same source and published within six weeks on either side of this one. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.

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