| Title |
Harsh Discipline, Childhood Sexual Assault, and MAOA Genotype: An Investigation of Main and Interactive Effects on Diverse Clinical Externalizing Outcomes
|
|---|---|
| Published in |
Behavior Genetics, April 2010
|
| DOI | 10.1007/s10519-010-9358-9 |
| Pubmed ID | |
| Authors |
Jaime Derringer, Robert F. Krueger, Daniel E. Irons, William G. Iacono |
| Abstract |
We studied the impact of MAOA genotype, childhood sexual assault, and harsh discipline on clinical externalizing symptoms (substance problems, adult antisocial behavior, and conduct disorder). Participants were 841 individual twins from the Minnesota Twin Family Study assessed through age 25. MAOA genotype was not associated with differences in any phenotype, nor was there a significant interaction between MAOA and harsh discipline for any phenotype or a significant interaction between MAOA and childhood sexual assault for substance problems. We found evidence that childhood sexual assault interacted with MAOA genotype to predict antisocial behavior and conduct disorder symptoms. Individuals with the low MAOA activity genotype who reported childhood sexual assault had more symptoms than individuals with either the high MAOA activity genotype and/or no history of childhood sexual assault. These findings suggest that the previously reported interaction between MAOA and childhood maltreatment may be specific to the antisocial subset of externalizing disorders. |
Mendeley readers
The data shown below were compiled from readership statistics for 105 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 3% |
| Finland | 1 | <1% |
| Spain | 1 | <1% |
| United Kingdom | 1 | <1% |
| Unknown | 99 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 20 | 19% |
| Student > Ph. D. Student | 13 | 12% |
| Researcher | 12 | 11% |
| Student > Doctoral Student | 10 | 10% |
| Student > Bachelor | 10 | 10% |
| Other | 20 | 19% |
| Unknown | 20 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 47 | 45% |
| Medicine and Dentistry | 10 | 10% |
| Social Sciences | 9 | 9% |
| Nursing and Health Professions | 3 | 3% |
| Agricultural and Biological Sciences | 3 | 3% |
| Other | 6 | 6% |
| Unknown | 27 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 January 2012.
All research outputs
#7,429,612
of 22,714,025 outputs
Outputs from Behavior Genetics
#367
of 908 outputs
Outputs of similar age
#34,606
of 95,258 outputs
Outputs of similar age from Behavior Genetics
#5
of 6 outputs
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