| Title |
Involvement of 5HT1A receptors in the anxiolytic-like effects of cannabidiol injected into the dorsolateral periaqueductal gray of rats
|
|---|---|
| Published in |
Psychopharmacology, May 2008
|
| DOI | 10.1007/s00213-008-1168-x |
| Pubmed ID | |
| Authors |
Alline Cristina Campos, Francisco Silveira Guimarães |
| Abstract |
Cannabidiol (CBD) is a non-psychotomimetic constituent of Cannabis sativa plant that induces anxiolytic effects. However, the brain sites and mechanisms of these effects remain poorly understood. The dorsolateral periaqueductal gray (dlPAG) is a midbrain structure related to anxiety that contains receptors proposed to interact with CBD such as 5HT1A. In addition, since CBD has been shown to inhibit anandamide metabolism, CB1 receptors could also be involved in the effects of this cannabinoid. |
Mendeley readers
The data shown below were compiled from readership statistics for 280 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 1% |
| Italy | 2 | <1% |
| Brazil | 2 | <1% |
| United Kingdom | 2 | <1% |
| Spain | 1 | <1% |
| Czechia | 1 | <1% |
| Unknown | 269 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 53 | 19% |
| Student > Ph. D. Student | 45 | 16% |
| Researcher | 39 | 14% |
| Student > Master | 32 | 11% |
| Professor | 10 | 4% |
| Other | 36 | 13% |
| Unknown | 65 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 40 | 14% |
| Pharmacology, Toxicology and Pharmaceutical Science | 39 | 14% |
| Agricultural and Biological Sciences | 38 | 14% |
| Medicine and Dentistry | 21 | 8% |
| Biochemistry, Genetics and Molecular Biology | 18 | 6% |
| Other | 44 | 16% |
| Unknown | 80 | 29% |
Attention Score in Context
This research output has an Altmetric Attention Score of 51. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 May 2021.
All research outputs
#848,763
of 26,017,215 outputs
Outputs from Psychopharmacology
#219
of 5,442 outputs
Outputs of similar age
#1,604
of 92,966 outputs
Outputs of similar age from Psychopharmacology
#2
of 27 outputs
Altmetric has tracked 26,017,215 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 5,442 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.0. This one has done particularly well, scoring higher than 95% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 92,966 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 27 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 92% of its contemporaries.