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Spatiotemporal evolution of venous narrowing in acute MS lesions

Overview of attention for article published in Neurology: Neuroimmunology and Neuroinflammation, January 2018
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Title
Spatiotemporal evolution of venous narrowing in acute MS lesions
Published in
Neurology: Neuroimmunology and Neuroinflammation, January 2018
DOI 10.1212/nxi.0000000000000440
Pubmed ID
Authors

Philipp Eisele, Kristina Szabo, Anne Ebert, Wolfgang Brueck, Michael Platten, Achim Gass

Abstract

To investigate the spatiotemporal evolution of venous narrowing in newly developing MS lesions in a longitudinal MRI study including susceptibility-weighted images (SWIs). We retrospectively investigated serial MR examinations of 18 patients with MS acquired on a 3T MRI system including SWI for acute contrast-enhancing lesions with at least 1 MRI examination before contrast enhancement. The mean diameter of veins at the time point of contrast enhancement was compared with the mean diameter of veins before and after contrast enhancement. A total of 40 acute contrast-enhancing lesions with a corresponding intralesional central vein were included in the study. The mean diameter of intralesional veins at the time of contrast enhancement (0.80 ± 0.12 mm) was smaller than that at before (1.16 ± 0.19 mm) and after contrast enhancement (1.07 ± 0.15 mm; p < 0.001 for all comparisons). Our findings contribute to the increasing database of plaque development and evolution. The smaller diameter of intralesional veins on SWI at the time of blood-brain barrier breakdown may reflect morphologic changes because of perivascular inflammation and/or decreased levels of deoxygenated hemoglobin.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 13 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 13 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 3 23%
Student > Master 3 23%
Student > Ph. D. Student 2 15%
Student > Bachelor 1 8%
Student > Doctoral Student 1 8%
Other 2 15%
Unknown 1 8%
Readers by discipline Count As %
Medicine and Dentistry 4 31%
Psychology 2 15%
Agricultural and Biological Sciences 1 8%
Immunology and Microbiology 1 8%
Physics and Astronomy 1 8%
Other 1 8%
Unknown 3 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 April 2018.
All research outputs
#14,741,795
of 25,604,262 outputs
Outputs from Neurology: Neuroimmunology and Neuroinflammation
#1,001
of 1,184 outputs
Outputs of similar age
#225,050
of 452,670 outputs
Outputs of similar age from Neurology: Neuroimmunology and Neuroinflammation
#26
of 29 outputs
Altmetric has tracked 25,604,262 research outputs across all sources so far. This one is in the 41st percentile – i.e., 41% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,184 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 20.9. This one is in the 14th percentile – i.e., 14% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 452,670 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 49th percentile – i.e., 49% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 29 others from the same source and published within six weeks on either side of this one. This one is in the 6th percentile – i.e., 6% of its contemporaries scored the same or lower than it.