Title |
Prevention of postoperative swelling and pain by dexamethasone after operative removal of impacted third molar teeth
|
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Published in |
European Journal of Clinical Pharmacology, March 1993
|
DOI | 10.1007/bf00271371 |
Pubmed ID | |
Authors |
R. Schmelzeisen, J. -C. Frölich |
Abstract |
In a placebo-controlled double-blind study, we examined the effect of perioperative oral administration of 6 mg dexamethasone, given once 12 h before and once 12 h after osteotomy of two impacted molar teeth, on postoperative edema, limitation of jaw opening, and intensity of postoperative pain. On the first day after surgery the difference in the increase in cheek swelling was 54.3% (P < 0.001) as measured with a tape, 46% (P < 0.001) measured with a gauge in the first molar area and 29% (P < or = 0.056) by sonographic measurement of the cheek diameter in the molar area. The limitation in the jaw opening was reduced by 17.7% (P < 0.002) after dexamethasone. Pain assessed by visual analog scale was reduced by dexamethasone by 50% (P < 0.01). The amount of analgesics required postoperatively (codeine phosphate) was reduced by 37% (P = 0.02) following dexamethasone administration. Seventy-six percent of our patients preferred perioperative medication of dexamethasone. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 64 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 13 | 20% |
Student > Postgraduate | 8 | 13% |
Other | 6 | 9% |
Student > Bachelor | 4 | 6% |
Unspecified | 4 | 6% |
Other | 11 | 17% |
Unknown | 18 | 28% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 33 | 52% |
Unspecified | 4 | 6% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 3% |
Chemical Engineering | 2 | 3% |
Chemistry | 2 | 3% |
Other | 2 | 3% |
Unknown | 19 | 30% |