| Title |
Characterization of Salmonella enterica from invasive bloodstream infections and water sources in rural Ghana
|
|---|---|
| Published in |
BMC Infectious Diseases, January 2018
|
| DOI | 10.1186/s12879-018-2957-4 |
| Pubmed ID | |
| Authors |
Denise Dekker, Ralf Krumkamp, Daniel Eibach, Nimako Sarpong, Kennedy Gyau Boahen, Michael Frimpong, Elina Fechtner, Sven Poppert, Ralf Matthias Hagen, Norbert Georg Schwarz, Yaw Adu-Sarkodie, Ellis Owusu-Dabo, Justin Im, Florian Marks, Hagen Frickmann, Jürgen May |
| Abstract |
Non-typhoidal Salmonella (NTS) cause the majority of bloodstream infections in Ghana, however the mode of transmission and source of invasive NTS in Africa are poorly understood. This study compares NTS from water sources and invasive bloodstream infections in rural Ghana. Blood from hospitalised, febrile children and samples from drinking water sources were analysed for Salmonella spp. Strains were serotyped to trace possible epidemiological links between human and water-derived isolates.. Antibiotic susceptibility testing was performed, RESULTS: In 2720 blood culture samples, 165 (6%) NTS were isolated. S. Typhimurium (70%) was the most common serovar followed by S. Enteritidis (8%) and S. Dublin (8%). Multidrug resistance (MDR) was found in 95 (58%) NTS isolates, including five S. Enteritidis. One S. Typhimurium showed reduced fluroquinolone susceptibility. In 511 water samples, 19 (4%) tested positive for S. enterica with two isolates being resistant to ampicillin and one isolate being resistant to cotrimoxazole. Serovars from water samples were not encountered in any of the clinical specimens. Water analyses demonstrated that common drinking water sources were contaminated with S. enterica posing a potential risk for transmission. However, a link between S. enterica from water sources and patients could not be established, questioning the ability of water-derived serovars to cause invasive bloodstream infections. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Venezuela, Bolivarian Republic of | 1 | 50% |
| United Kingdom | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 50% |
| Members of the public | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 119 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 119 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 16 | 13% |
| Student > Master | 16 | 13% |
| Student > Bachelor | 12 | 10% |
| Student > Ph. D. Student | 9 | 8% |
| Student > Postgraduate | 7 | 6% |
| Other | 14 | 12% |
| Unknown | 45 | 38% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 20 | 17% |
| Immunology and Microbiology | 13 | 11% |
| Biochemistry, Genetics and Molecular Biology | 10 | 8% |
| Agricultural and Biological Sciences | 9 | 8% |
| Environmental Science | 4 | 3% |
| Other | 13 | 11% |
| Unknown | 50 | 42% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 January 2018.
All research outputs
#17,926,658
of 23,016,919 outputs
Outputs from BMC Infectious Diseases
#5,165
of 7,723 outputs
Outputs of similar age
#310,333
of 441,339 outputs
Outputs of similar age from BMC Infectious Diseases
#101
of 164 outputs
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