| Title |
The human selenoproteome: recent insights into functions and regulation
|
|---|---|
| Published in |
Cellular and Molecular Life Sciences, April 2009
|
| DOI | 10.1007/s00018-009-0032-4 |
| Pubmed ID | |
| Authors |
M. A. Reeves, P. R. Hoffmann |
| Abstract |
Selenium (Se) is a nutritional trace mineral essential for various aspects of human health that exerts its effects mainly through its incorporation into selenoproteins as the amino acid, selenocysteine. Twenty-five selenoprotein genes have been identified in humans and several selenoproteins are broadly classified as antioxidant enzymes. As progress is made on characterizing the individual members of this protein family, however, it is becoming clear that their properties and functions are quite diverse. This review summarizes recent insights into properties of individual selenoproteins such as tissue distribution, subcellular localization, and regulation of expression. Also discussed are potential roles the different selenoproteins play in human health and disease. |
Mendeley readers
The data shown below were compiled from readership statistics for 240 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Turkey | 1 | <1% |
| Chile | 1 | <1% |
| India | 1 | <1% |
| Qatar | 1 | <1% |
| Spain | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 234 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 43 | 18% |
| Student > Master | 35 | 15% |
| Researcher | 28 | 12% |
| Student > Bachelor | 25 | 10% |
| Student > Doctoral Student | 19 | 8% |
| Other | 41 | 17% |
| Unknown | 49 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 78 | 33% |
| Biochemistry, Genetics and Molecular Biology | 33 | 14% |
| Medicine and Dentistry | 28 | 12% |
| Chemistry | 12 | 5% |
| Pharmacology, Toxicology and Pharmaceutical Science | 4 | 2% |
| Other | 21 | 9% |
| Unknown | 64 | 27% |
Attention Score in Context
This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 December 2022.
All research outputs
#3,460,684
of 23,794,258 outputs
Outputs from Cellular and Molecular Life Sciences
#571
of 4,151 outputs
Outputs of similar age
#11,769
of 94,785 outputs
Outputs of similar age from Cellular and Molecular Life Sciences
#2
of 39 outputs
Altmetric has tracked 23,794,258 research outputs across all sources so far. Compared to these this one has done well and is in the 84th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,151 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.0. This one has done well, scoring higher than 88% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 94,785 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 84% of its contemporaries.
We're also able to compare this research output to 39 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 92% of its contemporaries.