You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
Mendeley readers
Attention Score in Context
| Title |
Switching Akt: from survival signaling to deadly response
|
|---|---|
| Published in |
BioEssays, March 2009
|
| DOI | 10.1002/bies.200900005 |
| Pubmed ID | |
| Authors |
Marek Los, Subbareddy Maddika, Bettina Erb, Klaus Schulze‐Osthoff |
| Abstract |
Akt, a protein kinase hyperactivated in many tumors, plays a major role in both cell survival and resistance to tumor therapy. A recent study,1 along with other evidences, shows interestingly, that Akt is not a single-function kinase, but may facilitate rather than inhibit cell death under certain conditions. This hitherto undetected function of Akt is accomplished by its ability to increase reactive oxygen species and to suppress antioxidant enzymes. The ability of Akt to down-regulate antioxidant defenses uncovers a novel Achilles' heel, which could be exploited by oxidant therapies in order to selectively eradicate tumor cells that express high levels of Akt activity. |
Mendeley readers
The data shown below were compiled from readership statistics for 122 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 1 | <1% |
| United Kingdom | 1 | <1% |
| United States | 1 | <1% |
| Singapore | 1 | <1% |
| Unknown | 118 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 24 | 20% |
| Student > Ph. D. Student | 22 | 18% |
| Student > Master | 17 | 14% |
| Student > Bachelor | 10 | 8% |
| Student > Doctoral Student | 7 | 6% |
| Other | 22 | 18% |
| Unknown | 20 | 16% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 40 | 33% |
| Biochemistry, Genetics and Molecular Biology | 27 | 22% |
| Medicine and Dentistry | 17 | 14% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 2% |
| Neuroscience | 2 | 2% |
| Other | 8 | 7% |
| Unknown | 25 | 20% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 February 2019.
All research outputs
#8,535,684
of 25,374,917 outputs
Outputs from BioEssays
#1,341
of 3,015 outputs
Outputs of similar age
#37,900
of 106,860 outputs
Outputs of similar age from BioEssays
#11
of 23 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,015 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.3. This one is in the 33rd percentile – i.e., 33% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 106,860 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 17th percentile – i.e., 17% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 23 others from the same source and published within six weeks on either side of this one. This one is in the 13th percentile – i.e., 13% of its contemporaries scored the same or lower than it.