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DNA Replication

Overview of attention for book
Cover of 'DNA Replication'

Table of Contents

  1. Altmetric Badge
    Book Overview
  2. Altmetric Badge
    Chapter 1 Historical Perspective of Eukaryotic DNA Replication
  3. Altmetric Badge
    Chapter 2 Regulation of Replication Origins
  4. Altmetric Badge
    Chapter 3 Molecular Mechanism for Chromatin Regulation During MCM Loading in Mammalian Cells
  5. Altmetric Badge
    Chapter 4 Initiation of DNA Replication at the Chromosomal Origin of E. coli , oriC
  6. Altmetric Badge
    Chapter 5 Initiation of DNA Replication in the Archaea
  7. Altmetric Badge
    Chapter 6 Mechanism of Lagging-Strand DNA Replication in Eukaryotes
  8. Altmetric Badge
    Chapter 7 Functions of Multiple Clamp and Clamp-Loader Complexes in Eukaryotic DNA Replication
  9. Altmetric Badge
    Chapter 8 Termination of Eukaryotic Replication Forks
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    Chapter 9 Structure of the MCM2-7 Double Hexamer and Its Implications for the Mechanistic Functions of the Mcm2-7 Complex
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    Chapter 10 Architecture of the Saccharomyces cerevisiae Replisome
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    Chapter 11 Replication Domains: Genome Compartmentalization into Functional Replication Units
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    Chapter 12 Rif1-Dependent Regulation of Genome Replication in Mammals
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    Chapter 13 G-Quadruplexes and DNA Replication Origins
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    Chapter 14 Interaction of Rif1 Protein with G-Quadruplex in Control of Chromosome Transactions
  16. Altmetric Badge
    Chapter 15 Chromatin Replication and Histone Dynamics
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    Chapter 16 The Temporal Regulation of S Phase Proteins During G1
  18. Altmetric Badge
    Chapter 17 Roles of SUMO in Replication Initiation, Progression, and Termination
  19. Altmetric Badge
    Chapter 18 The Multiple Roles of Ubiquitylation in Regulating Challenged DNA Replication
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    Chapter 19 Regulation of Mammalian DNA Replication via the Ubiquitin-Proteasome System
  21. Altmetric Badge
    Chapter 20 Coordinating Replication with Transcription
  22. Altmetric Badge
    Chapter 21 Fragility Extraordinaire: Unsolved Mysteries of Chromosome Fragile Sites
  23. Altmetric Badge
    Chapter 22 Cyclin E Deregulation and Genomic Instability
  24. Altmetric Badge
    Chapter 23 Replication Through Repetitive DNA Elements and Their Role in Human Diseases
Attention for Chapter 19: Regulation of Mammalian DNA Replication via the Ubiquitin-Proteasome System
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Chapter title
Regulation of Mammalian DNA Replication via the Ubiquitin-Proteasome System
Chapter number 19
Book title
DNA Replication
Published in
Advances in experimental medicine and biology, January 2017
DOI 10.1007/978-981-10-6955-0_19
Pubmed ID
Book ISBNs
978-9-81-106954-3, 978-9-81-106955-0
Authors

Tarek Abbas, Anindya Dutta, Abbas, Tarek, Dutta, Anindya

Abstract

Proper regulation of DNA replication ensures the faithful transmission of genetic material essential for optimal cellular and organismal physiology. Central to this regulation is the activity of a set of enzymes that induce or reverse posttranslational modifications of various proteins critical for the initiation, progression, and termination of DNA replication. This is particularly important when DNA replication proceeds in cancer cells with elevated rates of genomic instability and increased proliferative capacities. Here, we describe how DNA replication in mammalian cells is regulated via the activity of the ubiquitin-proteasome system as well as the consequence of derailed ubiquitylation signaling involved in this important cellular activity.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 16 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 16 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 3 19%
Researcher 3 19%
Student > Bachelor 2 13%
Student > Master 1 6%
Student > Doctoral Student 1 6%
Other 0 0%
Unknown 6 38%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 7 44%
Business, Management and Accounting 1 6%
Agricultural and Biological Sciences 1 6%
Sports and Recreations 1 6%
Unknown 6 38%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 January 2018.
All research outputs
#20,461,148
of 23,018,998 outputs
Outputs from Advances in experimental medicine and biology
#3,986
of 4,960 outputs
Outputs of similar age
#356,235
of 421,314 outputs
Outputs of similar age from Advances in experimental medicine and biology
#414
of 490 outputs
Altmetric has tracked 23,018,998 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,960 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.1. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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We're also able to compare this research output to 490 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.