| Title |
Phototransduction in ganglion-cell photoreceptors
|
|---|---|
| Published in |
Pflügers Archiv - European Journal of Physiology, March 2007
|
| DOI | 10.1007/s00424-007-0242-2 |
| Pubmed ID | |
| Authors |
David M. Berson |
| Abstract |
A third class of photoreceptors has recently been identified in the mammalian retina. They are a rare cell type within the class of ganglion cells, which are the output cells of the retina. These intrinsically photosensitive retinal ganglion cells support a variety of physiological responses to daylight, including synchronization of circadian rhythms, modulation of melatonin release, and regulation of pupil size. The goal of this review is to summarize what is currently known concerning the cellular and biochemical basis of phototransduction in these cells. I summarize the overwhelming evidence that melanopsin serves as the photopigment in these cells and review the emerging evidence that the downstream signaling cascade, including the light-gated channel, might resemble those found in rhabdomeric invertebrate photoreceptors. |
Mendeley readers
The data shown below were compiled from readership statistics for 244 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 5 | 2% |
| Germany | 2 | <1% |
| Spain | 2 | <1% |
| Israel | 1 | <1% |
| United Kingdom | 1 | <1% |
| Brazil | 1 | <1% |
| China | 1 | <1% |
| Portugal | 1 | <1% |
| Japan | 1 | <1% |
| Other | 1 | <1% |
| Unknown | 228 | 93% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 58 | 24% |
| Researcher | 43 | 18% |
| Student > Master | 27 | 11% |
| Student > Bachelor | 21 | 9% |
| Professor > Associate Professor | 18 | 7% |
| Other | 46 | 19% |
| Unknown | 31 | 13% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 90 | 37% |
| Neuroscience | 32 | 13% |
| Medicine and Dentistry | 25 | 10% |
| Biochemistry, Genetics and Molecular Biology | 20 | 8% |
| Engineering | 13 | 5% |
| Other | 30 | 12% |
| Unknown | 34 | 14% |
Attention Score in Context
This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 April 2024.
All research outputs
#5,690,774
of 23,815,455 outputs
Outputs from Pflügers Archiv - European Journal of Physiology
#222
of 1,973 outputs
Outputs of similar age
#15,259
of 77,746 outputs
Outputs of similar age from Pflügers Archiv - European Journal of Physiology
#4
of 13 outputs
Altmetric has tracked 23,815,455 research outputs across all sources so far. Compared to these this one has done well and is in the 76th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,973 research outputs from this source. They receive a mean Attention Score of 5.0. This one has done well, scoring higher than 83% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 77,746 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.