Title |
Markers that discriminate between European and African ancestry show limited variation within Africa
|
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Published in |
Human Genetics, September 2002
|
DOI | 10.1007/s00439-002-0818-z |
Pubmed ID | |
Authors |
Heather E. Collins-Schramm, Rick A. Kittles, Darwin J. Operario, James L. Weber, Lindsey A. Criswell, Richard S. Cooper, Michael F. Seldin |
Abstract |
Markers informative for ancestry are necessary for admixture mapping and improving case-control association analyses. In particular, African Americans are an admixed population for which genetic studies require accurately evaluating admixture. This will require markers that can be used in African Americans to determine if a given genomic region is of European or African ancestry. This report shows that, despite studies indicating high intra-African sequence variation, markers with large inter-ethnic differences have only small variations in allele distribution among divergent African populations and should be valuable for evaluating admixture in complex disease genetic studies. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United States | 2 | 6% |
Canada | 1 | 3% |
Unknown | 30 | 91% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 7 | 21% |
Researcher | 7 | 21% |
Professor | 4 | 12% |
Other | 3 | 9% |
Student > Master | 3 | 9% |
Other | 7 | 21% |
Unknown | 2 | 6% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 11 | 33% |
Medicine and Dentistry | 6 | 18% |
Biochemistry, Genetics and Molecular Biology | 4 | 12% |
Arts and Humanities | 2 | 6% |
Neuroscience | 2 | 6% |
Other | 5 | 15% |
Unknown | 3 | 9% |