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Anti-cancer gold(I) phosphine complexes: Cyclic trimers and tetramers containing the P-Au-P moiety

Overview of attention for article published in Journal of Inorganic Biochemistry, June 2017
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (52nd percentile)
  • Good Attention Score compared to outputs of the same age and source (75th percentile)

Mentioned by

patent
3 patents

Citations

dimensions_citation
28 Dimensions

Readers on

mendeley
37 Mendeley
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Title
Anti-cancer gold(I) phosphine complexes: Cyclic trimers and tetramers containing the P-Au-P moiety
Published in
Journal of Inorganic Biochemistry, June 2017
DOI 10.1016/j.jinorgbio.2017.06.010
Pubmed ID
Authors

T. Srinivasa Reddy, Steven H. Privér, Nedaossadat Mirzadeh, Suresh K. Bhargava

Abstract

We report the application of cationic tri- and tetra-nuclear gold(I) phosphine complexes [Au3(μ-dppen)3]X3 and [Au4(μ-dppa)4]X4 (X=OTf, PF6) [OTf=trifluoromethanesulfonate, dppen=trans-1,2-bis(diphenylphosphino)ethene, dppa=bis(diphenylphosphino)acetylene] for cancer treatment. The results of cytotoxicity tests on four different cancer cells [prostate (DU145), cervical (HeLa), breast (MDAMB-231) and fibro sarcoma (HT1080)] indicate these complexes possess remarkable tumor cell growth inhibitory effects and high selectivity towards cancer cells. The anti-tumor mechanism of the tri- and tetra-nuclear gold(I) complexes has also been investigated.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 37 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 37 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 8 22%
Student > Ph. D. Student 6 16%
Professor > Associate Professor 4 11%
Student > Bachelor 4 11%
Other 1 3%
Other 2 5%
Unknown 12 32%
Readers by discipline Count As %
Chemistry 14 38%
Medicine and Dentistry 4 11%
Materials Science 2 5%
Earth and Planetary Sciences 1 3%
Arts and Humanities 1 3%
Other 2 5%
Unknown 13 35%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 December 2019.
All research outputs
#8,537,346
of 25,382,440 outputs
Outputs from Journal of Inorganic Biochemistry
#511
of 1,921 outputs
Outputs of similar age
#127,076
of 328,389 outputs
Outputs of similar age from Journal of Inorganic Biochemistry
#4
of 24 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,921 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.2. This one is in the 41st percentile – i.e., 41% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 328,389 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 52% of its contemporaries.
We're also able to compare this research output to 24 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 75% of its contemporaries.