| Title |
The clinical management of BRCA1 and BRCA2 mutation carriers
|
|---|---|
| Published in |
Current Oncology Reports, February 2008
|
| DOI | 10.1007/s11912-008-0008-9 |
| Pubmed ID | |
| Authors |
Anthony P. Gulati, Susan M. Domchek |
| Abstract |
Mutations in the cancer susceptibility genes BRCA1 and BRCA2 are associated with significantly increased risks of breast and ovarian cancer. Fortunately, effective strategies are available to reduce these risks, including genetic testing, which is an important consideration in determining management of patients with a strong family history of cancer. This article reviews the current evidence for risk-reducing strategies in BRCA1 and BRCA2 mutation carriers and outlines future research directions. In particular, screening controversies and current guidelines are discussed, as are issues related to prophylactic mastectomy and oophorectomy. |
Mendeley readers
The data shown below were compiled from readership statistics for 45 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 45 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 10 | 22% |
| Student > Master | 7 | 16% |
| Student > Ph. D. Student | 6 | 13% |
| Researcher | 4 | 9% |
| Student > Postgraduate | 4 | 9% |
| Other | 7 | 16% |
| Unknown | 7 | 16% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 15 | 33% |
| Agricultural and Biological Sciences | 7 | 16% |
| Biochemistry, Genetics and Molecular Biology | 5 | 11% |
| Nursing and Health Professions | 3 | 7% |
| Chemistry | 3 | 7% |
| Other | 3 | 7% |
| Unknown | 9 | 20% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 September 2020.
All research outputs
#8,511,458
of 25,381,864 outputs
Outputs from Current Oncology Reports
#370
of 984 outputs
Outputs of similar age
#46,948
of 172,709 outputs
Outputs of similar age from Current Oncology Reports
#1
of 4 outputs
Altmetric has tracked 25,381,864 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 984 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.4. This one is in the 47th percentile – i.e., 47% of its peers scored the same or lower than it.
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We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them