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Phase 2 Study of Temozolomide-Based Chemoradiation Therapy for High-Risk Low-Grade Gliomas: Preliminary Results of Radiation Therapy Oncology Group 0424

Overview of attention for article published in International Journal of Radiation Oncology, Biology, Physics, January 2015
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (98th percentile)
  • High Attention Score compared to outputs of the same age and source (98th percentile)

Mentioned by

news
12 news outlets
policy
1 policy source
twitter
18 X users
patent
1 patent
facebook
7 Facebook pages

Citations

dimensions_citation
139 Dimensions

Readers on

mendeley
163 Mendeley
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Title
Phase 2 Study of Temozolomide-Based Chemoradiation Therapy for High-Risk Low-Grade Gliomas: Preliminary Results of Radiation Therapy Oncology Group 0424
Published in
International Journal of Radiation Oncology, Biology, Physics, January 2015
DOI 10.1016/j.ijrobp.2014.11.012
Pubmed ID
Authors

Barbara J. Fisher, Chen Hu, David R. Macdonald, Glenn J. Lesser, Stephen W. Coons, David G. Brachman, Samuel Ryu, Maria Werner-Wasik, Jean-Paul Bahary, Junfeng Liu, Arnab Chakravarti, Minesh Mehta

Abstract

Radiation Therapy Oncology Group (RTOG) 0424 was a phase 2 study of a high-risk low-grade glioma (LGG) population who were treated with temozolomide (TMZ) and radiation therapy (RT), and outcomes were compared to those of historical controls. This study was designed to detect a 43% increase in median survival time (MST) from 40.5 to 57.9 months and a 20% improvement in 3-year overall survival (OS) rate from 54% to 65% at a 10% significance level (1-sided) and 96% power.

X Demographics

X Demographics

The data shown below were collected from the profiles of 18 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 163 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 3 2%
Unknown 160 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 29 18%
Other 23 14%
Student > Postgraduate 22 13%
Student > Ph. D. Student 16 10%
Student > Doctoral Student 13 8%
Other 32 20%
Unknown 28 17%
Readers by discipline Count As %
Medicine and Dentistry 88 54%
Neuroscience 7 4%
Chemistry 4 2%
Nursing and Health Professions 3 2%
Physics and Astronomy 3 2%
Other 15 9%
Unknown 43 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 108. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 July 2021.
All research outputs
#394,347
of 25,576,801 outputs
Outputs from International Journal of Radiation Oncology, Biology, Physics
#114
of 11,129 outputs
Outputs of similar age
#4,792
of 362,566 outputs
Outputs of similar age from International Journal of Radiation Oncology, Biology, Physics
#1
of 86 outputs
Altmetric has tracked 25,576,801 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 11,129 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 362,566 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 86 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 98% of its contemporaries.