| Title |
Advancing biotechnology with CRISPR/Cas9: recent applications and patent landscape
|
|---|---|
| Published in |
Journal of Industrial Microbiology & Biotechnology, July 2018
|
| DOI | 10.1007/s10295-017-2000-6 |
| Pubmed ID | |
| Authors |
Raphael Ferreira, Florian David, Jens Nielsen |
| Abstract |
Clustered regularly interspaced short palindromic repeats (CRISPR) is poised to become one of the key scientific discoveries of the twenty-first century. Originating from prokaryotic and archaeal immune systems to counter phage invasions, CRISPR-based applications have been tailored for manipulating a broad range of living organisms. From the different elucidated types of CRISPR mechanisms, the type II system adapted from Streptococcus pyogenes has been the most exploited as a tool for genome engineering and gene regulation. In this review, we describe the different applications of CRISPR/Cas9 technology in the industrial biotechnology field. Next, we detail the current status of the patent landscape, highlighting its exploitation through different companies, and conclude with future perspectives of this technology. |
X Demographics
The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 14% |
| United Kingdom | 1 | 14% |
| Unknown | 5 | 71% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 5 | 71% |
| Scientists | 2 | 29% |
Mendeley readers
The data shown below were compiled from readership statistics for 152 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 152 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 26 | 17% |
| Student > Ph. D. Student | 22 | 14% |
| Student > Master | 20 | 13% |
| Student > Bachelor | 16 | 11% |
| Student > Postgraduate | 9 | 6% |
| Other | 18 | 12% |
| Unknown | 41 | 27% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 52 | 34% |
| Agricultural and Biological Sciences | 24 | 16% |
| Engineering | 8 | 5% |
| Computer Science | 4 | 3% |
| Immunology and Microbiology | 4 | 3% |
| Other | 20 | 13% |
| Unknown | 40 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 20. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 August 2021.
All research outputs
#1,846,631
of 25,382,440 outputs
Outputs from Journal of Industrial Microbiology & Biotechnology
#17
of 1,612 outputs
Outputs of similar age
#37,846
of 341,606 outputs
Outputs of similar age from Journal of Industrial Microbiology & Biotechnology
#1
of 24 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,612 research outputs from this source. They receive a mean Attention Score of 4.4. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 341,606 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 24 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 95% of its contemporaries.