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Point-of-Care Urine Ethyl Glucuronide Testing to Detect Alcohol Use Among HIV-Hepatitis B Virus Coinfected Adults in Zambia

Overview of attention for article published in AIDS and Behavior, January 2018
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Title
Point-of-Care Urine Ethyl Glucuronide Testing to Detect Alcohol Use Among HIV-Hepatitis B Virus Coinfected Adults in Zambia
Published in
AIDS and Behavior, January 2018
DOI 10.1007/s10461-018-2030-8
Pubmed ID
Authors

Michael J. Vinikoor, Zude Zyambo, Monde Muyoyeta, Geetanjali Chander, Michael S. Saag, Karen Cropsey

Abstract

In an HIV-hepatitis B virus (HIV-HBV) coinfection cohort in Zambia, we piloted a qualitative point-of-care (POC) test for urine Ethyl glucuronide (uEtG), assessed concordance between uEtG and alcohol use disorders identification test-consumption (AUDIT-C), and identified epidemiological factors associated with underreporting (defined as uEtG-positivity with last reported drink > 7 days prior). Among 211 participants (40.8% women), there were 44 (20.8%) lifetime abstainers, 32 (15.2%) former drinkers, and 135 (64.0%) current drinkers, including 106 (50.2%) with unhealthy drinking per AUDIT-C. Eighty-seven (41.2%) were uEtG-positive including 64 of 65 (98.5%) who drank ≤ 3 days prior and 17 of 134 (12.7%) underreported, all of whom admitted to recent drinking when results were discussed. uEtG was moderately concordant with AUDIT-C. Past drinking (versus lifetime abstinence) and longer time on antiretrovirals (≥ 12 months) were associated with underreporting. These data support further use of POC alcohol biomarkers in HIV and hepatitis research and clinical settings.

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Mendeley readers

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Geographical breakdown

Country Count As %
Unknown 50 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 11 22%
Researcher 10 20%
Student > Ph. D. Student 4 8%
Other 3 6%
Student > Bachelor 2 4%
Other 4 8%
Unknown 16 32%
Readers by discipline Count As %
Medicine and Dentistry 11 22%
Nursing and Health Professions 7 14%
Psychology 4 8%
Unspecified 2 4%
Mathematics 2 4%
Other 7 14%
Unknown 17 34%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 February 2018.
All research outputs
#18,572,005
of 23,849,058 outputs
Outputs from AIDS and Behavior
#2,846
of 3,566 outputs
Outputs of similar age
#338,725
of 478,141 outputs
Outputs of similar age from AIDS and Behavior
#53
of 68 outputs
Altmetric has tracked 23,849,058 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
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