Title |
Donor Considerations in Fecal Microbiota Transplantation
|
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Published in |
Current Gastroenterology Reports, March 2017
|
DOI | 10.1007/s11894-017-0548-y |
Pubmed ID | |
Authors |
Danielle Barnes, K. T. Park |
Abstract |
Tremendous acceleration has been made in understanding the gut microbiota in the past decade and, with it, further understanding of the pathologic role of dysbiosis and the use of fecal microbiota transplantation (FMT) as therapy. FMT has been studied in many disease states including the most common indication of Clostridium difficile infection (CDI), though many questions regarding stool donor selection remain. Though traditionally, one donor has provided stool for one patient, research is underway to explore many donor selection considerations from the use of pooled donor stool to selection of a high diversity donor. It is well-known that dietary intake shapes the gut microbiota and the potential implications of this on FMT donor selection are being explored. Though further high-quality research is needed, optimizing the fecal microbiota inoculum holds great promise. |
X Demographics
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 78 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 12 | 15% |
Student > Bachelor | 10 | 13% |
Student > Ph. D. Student | 9 | 12% |
Student > Master | 7 | 9% |
Student > Doctoral Student | 4 | 5% |
Other | 12 | 15% |
Unknown | 24 | 31% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 26 | 33% |
Biochemistry, Genetics and Molecular Biology | 8 | 10% |
Immunology and Microbiology | 6 | 8% |
Agricultural and Biological Sciences | 4 | 5% |
Nursing and Health Professions | 4 | 5% |
Other | 6 | 8% |
Unknown | 24 | 31% |