Title |
Marker evaluation for differentiation of blood and menstrual fluid by methylation-sensitive SNaPshot analysis
|
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Published in |
International Journal of Legal Medicine, January 2018
|
DOI | 10.1007/s00414-018-1770-3 |
Pubmed ID | |
Authors |
Hannah Holtkötter, Kristina Schwender, Peter Wiegand, Heidi Pfeiffer, Marielle Vennemann |
Abstract |
The differentiation of blood and menstrual fluid is especially important in cases of alleged sexual assault. While the identification of blood is relatively straightforward, the identification of menstrual fluid in trace evidence has been shown to be more challenging. This may be due to the complex nature of menstrual fluid that leads to intra- and inter-individual differences in composition. Nevertheless, recent advances in DNA methylation profiling have revealed promising markers for the differentiation of the two body fluids and furthermore, markers to distinguish menstrual fluid from vaginal fluid. A literature study was performed and in total, 11 markers were evaluated in this study of which seven could be validated for menstrual fluid and blood identification purposes. Marker "BLU2" (chr16:29757334) was identified as most suitable for differentiation of blood and menstrual fluid. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Australia | 1 | 33% |
China | 1 | 33% |
Unknown | 1 | 33% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 67% |
Scientists | 1 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 24 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 6 | 25% |
Researcher | 5 | 21% |
Student > Bachelor | 3 | 13% |
Professor | 2 | 8% |
Student > Master | 2 | 8% |
Other | 2 | 8% |
Unknown | 4 | 17% |
Readers by discipline | Count | As % |
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Biochemistry, Genetics and Molecular Biology | 9 | 38% |
Chemistry | 3 | 13% |
Psychology | 2 | 8% |
Social Sciences | 2 | 8% |
Nursing and Health Professions | 1 | 4% |
Other | 1 | 4% |
Unknown | 6 | 25% |