Title |
Ectopic Cushing’s syndrome secondary to olfactory neuroblastoma
|
---|---|
Published in |
Acta Neurochirurgica, January 2018
|
DOI | 10.1007/s00701-017-3447-y |
Pubmed ID | |
Authors |
Kenny Yu, Federico Roncaroli, Tara Kearney, David Ewins, Deepa Beeharry, Thomas Naylor, David Ray, Rajiv Bhalla, Kanna Gnanalingham |
Abstract |
We present the case of a patient with Cushing's syndrome secondary to ectopic ACTH secretion. A MR of the head showed a left-sided nasal mass extending down from the cribriform plate. The patient underwent endoscopic resection with nearly complete removal of the mass. Histological examination showed an ACTH-secreting olfactory neuroblastoma (ONB). The patient's cortisol levels returned to normal range after surgery and have remained normal for over a year. ONB is a rare cause for ectopic ACTH secretion. This case highlights the diagnostic and management difficulties in patients with ectopic ACTH secretion, and provides a brief review of ONB. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Switzerland | 1 | 10% |
United Kingdom | 1 | 10% |
Italy | 1 | 10% |
United States | 1 | 10% |
Unknown | 6 | 60% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 5 | 50% |
Scientists | 3 | 30% |
Science communicators (journalists, bloggers, editors) | 1 | 10% |
Practitioners (doctors, other healthcare professionals) | 1 | 10% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 27 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Doctoral Student | 4 | 15% |
Researcher | 4 | 15% |
Student > Ph. D. Student | 3 | 11% |
Student > Bachelor | 3 | 11% |
Other | 2 | 7% |
Other | 2 | 7% |
Unknown | 9 | 33% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 8 | 30% |
Biochemistry, Genetics and Molecular Biology | 3 | 11% |
Nursing and Health Professions | 2 | 7% |
Arts and Humanities | 1 | 4% |
Agricultural and Biological Sciences | 1 | 4% |
Other | 1 | 4% |
Unknown | 11 | 41% |