Title |
腸内細菌叢と免疫の関わり
|
---|---|
Published in |
Immunological Medicine, January 2017
|
DOI | 10.2177/jsci.40.408 |
Pubmed ID | |
Authors |
Shun Tanemoto, Tomohisa Sujino, Takanori Kanai |
Abstract |
Human Intestine has a diverse population of bacteria which induces pathogens to disrupt not only the intestinal homeostasis but whole body immune systems. Dysbiosis, the abnormal proliferation and reduction of the microbiota, breaks down the homeostasis of the immunity and metabolisms in the host. The evolution of the microbiota analysis technology contributed to reveal the molecular biological complex interaction between the microbiota and its host systemically as well as locally. Because several diseases are caused by the dysbiosis, fecal transplantation would be the new therapeutic target for them. It has been investigated in some intestinal diseases such as CD infection, or inflammatory bowel disease. Here, we review these symbiotic interactions and the current state for the clinical application. |
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Geographical breakdown
Country | Count | As % |
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United States | 2 | 29% |
Unknown | 5 | 71% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 6 | 86% |
Scientists | 1 | 14% |
Mendeley readers
Geographical breakdown
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Unknown | 52 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 12 | 23% |
Student > Master | 7 | 13% |
Student > Ph. D. Student | 5 | 10% |
Student > Bachelor | 3 | 6% |
Professor | 3 | 6% |
Other | 9 | 17% |
Unknown | 13 | 25% |
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Medicine and Dentistry | 8 | 15% |
Biochemistry, Genetics and Molecular Biology | 8 | 15% |
Immunology and Microbiology | 8 | 15% |
Agricultural and Biological Sciences | 7 | 13% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 2% |
Other | 4 | 8% |
Unknown | 16 | 31% |